Process Analytics
Total Cell Density Reimagined
Our brand new Dencytee Arc sensors enable real-time, in-situ measurement of total cell density over the complete bioprocess. Thanks to its breakthrough measuring principle it delivers precise results in both low and high cell density concentrations. Guided in-line/off-line correlation modeling using the ArcAir software facilitates the creation of a total biomass sensor.
Reduce off-line sampling and increase the reliable optical density measurement range with Dencytee Arc.
Sensors for Single-Use
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Latest Innovations
Excellence means to go beyond average, to surpass, and to be of great value. It is at the core of our mission and defines Hamilton Process Analytics — who we are, what we do — our purpose.
Dencytee Arc
CO₂NTROL
Expanded Single-Use Portfolio
VisiFerm mA
Should CO2 Be a Critical Process Parameter?
Download Part 1 of our Dissolved CO2 White Paper Series to learn how implementing real-time control of Carbon Dioxide can impact productivity at R&D and production scale bioreactors.
Sensors Specifically for Single-Use
Hamilton's single-use pH sensors combine the reliability and measurement stability of our long-term proven conventional sensors with the ease of use as an integral part of the bioreactor. The sensors retain the high accuracy performance even after gamma irradiation and a sufficient shelf life making it the ideal single-use solution.
The Power of On-Line Intelligent Sensors
Traditional pH sensor management in a production process is costly and labor intensive — often the sensor only accounts for 20 percent of total operational costs. Hamilton’s Arc intelligent pH sensors redefine the relationship between sensors and transmitters, openning a wide range of operational process improvements and cost reduction.
Real-Time Cell Density Measurement for Real-Time Control
On-line, or in-situ, measurement is the pinnacle of process monitoring and necessary for true process control as evidenced with control of pH and dissolved oxygen, common for most biological processes. In fact, many parameters can be monitored but those directly related to cell physiology are typically time consuming off-line measurements that provide only a reactionary window into the past. Incyte Arc and Dencytee sensors provide a means for directly measuring viable cell density and total cell density in real-time, meeting the increasing need for PAT in the biopharmaceutical industry.
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Resources
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Brochure - BioPharma
Innovative solutions for process analytics in biotechnological and pharmaceutical industries. -
Brochure - Brewery
Learn about our control and analytical solutions that are essential to the brewing process. -
Confirmation of PFOA Regulations
A document that confirms Hamilton Bonaduz AG compiles with PFOA regulations related to EU Regulation 2019/1021 (POP) Annex I, Part A, and the REACH Regulation (Annex XVII, entry 68).
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Traditional vs. Arc vs. Memosens Sensors?
Traditional sensors provide standard mV output and rely on a separate transmitter or controller to amplify the signal and convert to an actual reading. Arc sensors provide a built-in microtransmitter that can output either 4 - 20mA or Modbus RTU digital communication. Finally Memosens sensors offer a digital signal that works with all Memosens transmitters and analyzers currently on the market. -
What is A-length and how is it measured?
A-length refers to the insertion depth of the sensor. It's generally measured from the base of the PG13.5 mounting threads but can vary with certain styles of sensors. -
What is the difference between pH and ORP?
pH and ORP sensors look alike but have different measurement principles. pH sensors rely on a glass membrane that produces a voltage signal in relation to the hydrogen ion concentration in the liquid. The concentration of acids or bases affect this hydrogen ion concentration thus influence the pH measurement. ORP sensors measure of the overall level of oxidizing or reducing substances present in the liquid. The ORP measurement is not specific to any single ion in the liquid thus the response is based on the net presence of these chemicals.
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Documentation and Certificates for Sensors and Liquid Solutions
What documentation and certificates can I expect with my sensor or probe? This article provides examples of the types of paper documents that normally come with Hamilton products. -
Common Questions for Autoclave Sterilization of Sensors
This brief article examines common questions from end-users about best practices for autoclaving Hamilton sensors.
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