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Hamilton Company has been developing and manufacturing pressure-stable polymeric high performance liquid chromatography (HPLC) columns for nearly 35 years. We are an established name in science whose products are found in most of the world’s top chromatography labs. From columns to syringes to septa and more, Hamilton Company offers a full line of off-the-shelf and custom chromatography products for HPLC and gas chromatography (GC).

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Hamilton reversed-phase HPLC columns combine the best characteristics of silica-based and polymeric columns to arrive at a product that is highly inert and long-lasting.

Anion Exchange

In anion exchange chromatography, the stationary bed has an ionically positive (+) charged surface while the sample ions are of negative (-) charge. The stronger the negative charge on the sample, the stronger it will be attracted to the positive charge on the stationary phase.

Cation Exchange

In cation exchange chromatography, the stationary bed has an ionically negative (-) charged surface while the sample ions are of positive (+) charge. This technique is used almost exclusively with ionic or ionizable samples.

Ion Exclusion

Ion exclusion chromatography is an alternative to ion exchange chromatography in which ionized samples are excluded from the pores of the support and elute first, while the weakly ionized and non-ionic compounds elute later.

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