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Hamilton offers 21 polymer-based stationary phases as well as two silica gels (C8 and C18) to satisfy most separation/purification needs. Our specialty resins are offered in a wide variety of hardware dimensions, and while these sizes cover many applications in varying science focuses, you may need a specific Hamilton resin in a column size we don't offer as off-the-shelf. Hamilton gives you control to build any column to your specifications with any of our stationary phases in any combination of our column hardware formats.

Create The Hamilton HPLC Column that Fits Your Application Needs

Click the appropriate part number below to configure and purchase your column!

HPLC Column ScaleInner DiameterLengthPart Number
Microbore1.0 mm / 2.1 mm50 mm, 100 mm, 150 mm, 250 mm79641
Analytical4.1 mm / 4.6 mm50 mm, 100 mm, 150 mm, 250 mm79641
Semipreparative7.0 mm / 7.8 mm / 10 mm50 mm, 100 mm, 150 mm, 250 mm, 300 mm*79642
Preparative21.2 mm / 30 mm50 mm, 100 mm, 150 mm, 250 mm79643
Preparative50 mm50 mm, 100 mm, 150 mm, 250 mm79644
Preparative100 mm50 mm, 100 mm, 150 mm, 250 mm79645

*Available for 7.0 mm and 7.8 mm ID hardware

Need Help Deciding Which Hamilton HPLC Column Is Right For You?

1. Choose your stationary phase

If you need additional information to determine which chemistry fits your application needs, check out our application index with over 1,700 compounds separated.

Search applications by stationary phase or compound of interest

Separation Mechanism

We specialize in polymer stationary phases and offer silica stationary phases covering the following separation mechanisms

Reversed-PhaseAnion Exchange
Cation ExchangeIon Exclusion

USP "L" Considerations

If you need to follow a specific USP monograph, browse our USP qualified stationary phases.

USP "L" Listings

2. Select the particle size and hardware dimensions

Choosing HPLC Column Specifications

3. We Build It!

We can repack your Hamilton HPLC column to perform like new using your existing column hardware

Need to Have Your Custom Hamilton HPLC Column Repacked?

Hamilton offers repacking services for your custom Hamilton HPLC column

HPLC Column ScaleInner DiameterRepack Part Number
Semipreparative7.0 mm / 7.8 mm / 10 mm79696
Preparative21.2 mm / 30 mm79697
Preparative50 mm79698
Preparative100 mm79699

Here's How It Works

1. Place an Order For The Needed Hardware Size/Scale (above)

2. Send Your HPLC Column Back To Hamilton

We'll work with you to ship your used HPLC column back to us using a traceable shipping method.

Fill out the RMA Form here and we'll get the process started.

3. Hamilton's Experts Will Take Care of The Rest!

Syringe Custom Built

Work with R&D engineers to customize Hamilton parts

Hamilton's "Custom Built" program puts you directly in contact with a Hamilton R&D Engineer to discuss your application and product needs. The engineer will point you to a standard solution or propose a customized solution to meet your needs.

Talk to an engineer