bioREACTOR 48 DS

pH
Real-Time Monitoring
Dissolved Oxygen (DO)
48 Parallel Reactors
High Batch Consistency
8–15 mL Working Volume
Scalable
Fully integrated Solution
Hands-Free

Accelerate Target Selection and Process Development

Highly parallel mini bioreactors and automated monitoring and processing help to significantly reduce development times so you can reach your goals faster.

Parallelized, Miniaturized Bioreactor System

The bioREACTOR 48 DS combines the advantages of highly parallelized microplate systems with the automated consistency of larger 100 mL scale bioreactors to facilitate high-throughput bacterial, yeast, and fungus culture. This device is ideal for strain screening and early process development and includes bioREACTOR technology from 2mag[1] .

The bioREACTOR 48 DS accommodates up to 48 cultures with 8–15 mL working volumes. With cultivation conditions very similar to those of stirred-tank bioreactors, it facilitates feeding (of individual cultures), temperature and gas regulation, and mixing while providing real-time, non-invasive pH (4–7.5 or 5.5–8.5) and DO (0–100%) monitoring.

Fully Integrated Automation

The seamless integration of the bioREACTOR 48 and Docking Station (DS) with the Microlab STAR automated liquid handler delivers complete control, real-time monitoring, and centralized management of microbial bioprocesses.

This setup enables automated regulation of pH, dissolved oxygen (DO), feeding, and sampling. Integration with third-party devices further extends automation capabilities and supports the measurement of critical parameters—essential for defining optimal process conditions early in development and enabling efficient scale-up to larger bioreactors. Multiple systems can be networked to significantly boost high-throughput, parallel bioprocessing.

Common applications Agri-Food and Beverage, Novel Food Bioprocessing, Precision Fermentation, Cultivated Meat, Pharma & Biopharma

Miniaturized, automated bioprocessing enables early identification of high-performing strains and optimal process conditions—accelerating development timelines and reducing overall costs.

Monitor and manage pH and DO in real-time via in-line sampling, even from a remote location using a networked computer.

Small-scale bioreactions conducted under conditions that closely mimic large-scale bioreactors—featuring enhanced oxygen transfer—enable seamless scale-up while reducing risk and cost.

Explore the bioreactor 48 DS

1

Optimized Culture Conditions

Controls temperature (10–50 °C), pH (4–7.5 or 5.5–8.5), DO (0–100%).
2

Standard Gassing Options

Accommodate aerobic and anaerobic cultures using air, O₂, N₂, and CO₂.
3

Stirring and Oxygen Transfer

Magnetic stirring bodies with a speed range of 100 to 4.000 rpm are used in the disposable, baffled culture vessels, and oxygen transfer rates are KLa 1440 h⁻¹ for high-performance cultivation.

bioREACTOR 48 DS Specifications

Docking Station for 2mag bioREACTOR 48 Specifications

System Dimensions

Height
9.76 m (32 ft, 0.45 in)
Width
2.4 m (7 ft, 10.49 in)
Length
3.67 m (12 ft, 0.49 in)

bioREACTOR 48 DS Resources

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