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Fighting rare or complex diseases without therapies developed by the biopharma industry is nowadays impossible. Recombinant proteins as well as simple amino acids for food supplement are produced using biotechnological methods. Therefore animal, or insect cells, bacteria, and yeast are genetically modified to produce the target molecules in commercially interesting amounts.


Research & Development

In R&D cell lines as well as bacteria and yeast strains are tested for their productivity of the target molecule. Plenty of bench-top bioreactors are used in parallel to generate the information in order to identify suitable lines or strains quickly.

Upstream Pilot & Production

With the help of animal cells, bacteria, yeast or algae the target molecules are formed during the upstream process. In the pilot phase the titer of the molecule is increased to very high levels. Therefore process conditions are optimized for the later production process.

Downstream Pilot & Production

Downstream processing is the most important procedure to isolate the target molecule efficiently and in high yields. Depending on the nature of the target molecule the process is optimized in the pilot phase to ensure a commercially successful production process.

Specific Applications

Should CO2 Be a Critical Process Parameter?

Download Part 1 of our Dissolved CO2 White Paper Series to learn how implementing real-time control of Carbon Dioxide can impact productivity at R&D and production scale bioreactors.


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