Biopharmaceutical
Fighting rare or complex diseases without therapies developed by the biopharma industry is nowadays impossible. Recombinant proteins as well as simple amino acids for food supplement are produced using biotechnological methods. Therefore animal, or insect cells, bacteria, and yeast are genetically modified to produce the target molecules in commercially interesting amounts.
Industries
Research & Development
In R&D cell lines as well as bacteria and yeast strains are tested for their productivity of the target molecule. Plenty of bench-top bioreactors are used in parallel to generate the information in order to identify suitable lines or strains quickly.
Upstream Pilot & Production
With the help of animal cells, bacteria, yeast or algae the target molecules are formed during the upstream process. In the pilot phase the titer of the molecule is increased to very high levels. Therefore process conditions are optimized for the later production process.
Downstream Pilot & Production
Downstream processing is the most important procedure to isolate the target molecule efficiently and in high yields. Depending on the nature of the target molecule the process is optimized in the pilot phase to ensure a commercially successful production process.
Specific Applications
-
App Note - Xylitol fermentation
Learn how Hamilton pH, DO, and cell density sensor technology helps the Budapest University of Technology and Economics work with different yeast strains to optimize xylitol yield. -
App Note - Online monitoring of CHO cell culture
A suite of Hamilton sensors is used to continuously monitor batch fermentation of CHO cells for tighter process control. -
App Note - Real-time total cell density measurement of yeast fermentations
Dencytee is used to optimize fermentation conditions for yeast processing. -
App Note - Arc pH and DO sensors in veterinary vaccine production
Hipra, an animal health company, based in Spain uses Modbus communication to integrate Arc sensors directly into their bioreactor installations.
We're Ready to Help
Hamilton's sales, customer service, and technical support staff are available for questions and additional information about all products and services.
Contact Us