Biopharmaceutical | Bio Pharma Industry

Fighting rare or complex diseases without therapies developed by the biopharma industry is nowadays impossible. Recombinant proteins as well as simple amino acids for food supplement are produced using biotechnological methods. Therefore animal, or insect cells, bacteria, and yeast are genetically modified to produce the target molecules in commercially interesting amounts.

Research & Development

In R&D cell lines as well as bacteria and yeast strains are tested for their productivity of the target molecule. Plenty of bench-top bioreactors are used in parallel to generate the information in order to identify suitable lines or strains quickly.

Upstream Pilot & Production

With the help of animal cells, bacteria, yeast or algae the target molecules are formed during the upstream process. In the pilot phase the titer of the molecule is increased to very high levels. Therefore process conditions are optimized for the later production process.

Solutions for Biopharma Downstream

Downstream processing is the most important procedure to isolate the target molecule efficiently. Due to its complexity, tight control of the downstream process is key to a successful production and high yield. With Hamilton's in-line sensors, you can keep control of critical process parameters in each production step.

Specific Applications

Featured Application

App Note - Real-time cell density measurement for PAT applications

An application highlighting the use of Incyte and Dencytee in a PAT approach to monoclonal antibody (mAb) production.

App Note - Real-time DO control thanks to optical sensors

Bioprocess Optimization thanks to Reliable In-line Monitoring
App Note - Xylitol fermentation

Learn how Hamilton pH, DO, and cell density sensor technology helps the Budapest University of Technology and Economics work with different yeast strains to optimize xylitol yield.
App Note - Online monitoring of CHO cell culture

A suite of Hamilton sensors is used to continuously monitor batch fermentation of CHO cells for tighter process control.
App Note - Real-time total cell density measurement of yeast fermentations

Dencytee is used to optimize fermentation conditions for yeast processing.

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Ready to Unlock the Secrets of Efficient Biopharma Downstream Processes?

Download out comprehensive white paper and gain valuable insights into the critical process parameters and advance sensor technologies that can revolutionize your biopharma downstream process (DSP). Discover strategies and techniques to optimize efficiency, improve product quality, and ensure the safety and efficacy of your biopharmaceutical products. Are you ready to take your downstream process to the next level? Get your copy and unlock the secrets for success.

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Should CO₂ Be a Critical Process Parameter?

Download Part 1 of our Dissolved CO₂ White Paper Series to learn how implementing real-time control of Carbon Dioxide can impact productivity at R&D and production scale bioreactors.

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Brochure - BioPharma

Innovative solutions for process analytics in biotechnological and pharmaceutical industries.

Upcoming Events

Process Analytics: BioSpain (Barcelona, Spain)

Barcelona, Spain

BIOSPAIN is the largest biotech event organized by a national bioindustry association in Europe.

Process Analytics: Forum A3P (Charleroi, Belgium)

Charleroi, Belgium

Forum A3P

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