Upstream Pilot & Production
Based on the results of R&D department the process conditions of growing cells, bacteria or yeast are further optimized in pilot scale reactors in order to increase yield and to simulate the conditions of the production process. Depending on the quantities needed the size of the bioreactors might vary by magnitudes.
Applications
Processes
Media Preparation
Media for cell culture or fermentation are prepared in a sterile environment and monitored carefully in order to get reliable results in the upstream process.
Pilot Seed Tank
Like in research & development cells, bacteria or yeast are kept under excellent growth conditions to maximize the yield of the target molecule in the large scale bioreactors in pilot and production departments.
Pilot Bioreactor
Aerobic or anaerobic processes are run the mainly stainless steel bioreactors to produce small or large molecules. In pilot scale reactors the process conditions for the later production size are determined and optimized.
Harvest Tank
Prior to further processing cell culture or fermentation broth from several bioreactors are collected in the harvest tank.
Specific Applications
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App Note - Real-time DO control thanks to optical sensors
Bioprocess Optimization thanks to Reliable In-line Monitoring -
App Note - Arc sensors in oncologic and biosimilar applications
Innoxtorres, a Spanish bioreactor manufacturer took advantage of Arc sensor technology to integrate EasyFerm Plus and VisiFerm DO sensors directly into their control system. -
App Note - Arc pH and DO sensors in veterinary vaccine production
Hipra, an animal health company, based in Spain uses Modbus communication to integrate Arc sensors directly into their bioreactor installations. -
App Note - Arc DO, pH, Cond in production scale fermentation process
GEA, a global equipment and process technology provider, integrates Arc sensor technology in fermentation plants at their GEA Diessel subsidiary in Hildesheim, Germany.
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