Real-Time. Solid State. Made for Bioproduction.
Hamilton's CO₂NTROL is a solid-state sensor that directly measures DCO₂ and provides maintenance free, real-time, and in-line control of this important critical process parameter. Get automated control that enables increased titer, better batch-to-batch reproducibility, and more consistency from R&D to production-scale bioreactors.
CO₂ Measurement Principles:
CO₂ molecules diffuse through a gas permeable membrane into an electrolyte. CO₂ increases the acidity of the electrolyte which is measured by an internal pH sensor.
CO₂NTROL Optical Measurement
CO₂ molecules diffuse into a gas permeable membrane where the sensor measures the absorption of CO₂-specific MID IR wavelengths. This absorption correlates to the partial pressure of CO₂ in the media.
CO₂NTROL is the newest member to Hamilton’s Arc Intelligent Sensor line. Embedded electronics convert the MIR CO₂ measurement into standard digital and analog signals that are easily integrated into your control strategy.
1. WIRELESS CONNECTIVITY
An optional Bluetooth adapter enables wireless calibration, configuration, and monitoring of all sensor details.
2. INTEGRATED INTELLIGENCE
Arc sensors save space and cost with integrated micro-transmitters that store calibration and sensor quality data.
3. PROCESS DATA
The sensor transmits process data through a hard-wired connection. Communication options include modbus RTU and 4–20 mA.
4. COMPLIANT HYGIENIC DESIGN
The hygienic design makes it compliant with requirements of biopharma applications.
No Ammonia Fouling
Brochure - Real-Time CO₂NTROL
What is the output signal of the CO₂NTROL Sensor?
What should CO₂NTROL be reading in air?The measurement range of the CO2NTROL sensor is 0.5 to 100% CO2 volume which is suitable for cell culture applications. The normal level of CO2 in air is approximately 0.04% which is technically below the measurement range of the sensor. Since the CO2 value is outside of the sensor measurement range, the error will be significant and the reading may appear to be noisy. Please note that this is acceptable and one of the reasons that air is used as a calibration point.
Is the CO₂NTROL CO₂ sensor sanitary?The tip of the CO2NTROL sensor has round "dots" that give the appearance of perforated metal. This surface is actually smooth. It is covered with a layer of translucent silicone that ensures a sanitary design. In fact, the design meets EHEDG sanitary requirements and has been certified.
What spare parts are needed for the CO₂NTROL Sensor?The CO2NTROL Sensor is completely sealed has no spare parts requirements for general operation. The EPDM o-ring seal on the exterior of the 12mm shaft is replaceable (Ref 254170).
White Paper: Are Current Dissolved CO₂ Measurement Technologies Good Enough?
CO₂NTROL RS485 Sensor CalibrationSince CO2 measurement can be a new parameter for some users this article provides some basic question and answer topics related to calibration of this sensor.
Cleaning Procedure for CO₂NTROL SensorsThis brief article highlights the manual cleaning process for the solid state sensing element used in the CO2NTROL RS485 CO2 Sensor.
White Paper: Dissolved CO₂ (pCO₂) at the BioreactorDissolved CO₂ (DCO₂ or pCO₂) is a critical process parameter (CPP) in biopharma production processes. By influencing other culture parameters such as extracellular and intracellular pH or key performance indicators such as viable cell density, it has a direct impact on product titer and its critical quality attributes.
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