Research & Development
In R&D cell lines as well as bacteria and yeast strains are tested for their productivity of the target molecule. Plenty of bench-top bioreactors are used in parallel to generate the information in order to identify suitable lines or strains quickly.
Bioreactors in Research & Development departments produce small amounts of target molecules. First process optimization steps are carried out to increase the yield of target molecules.
In the seed tank cells, bacteria or yeast are stored under nearly perfect conditions in order to keep a maximum of viable cells for the upstream process in the bioreactor.
App Note - Online monitoring of CHO cell culture
App Note - Real-time cell density measurement for PAT applicationsAn application highlighting the use of Incyte and Dencytee in a PAT approach to monoclonal antibody (mAb) production.
App Note - Xylitol fermentationLearn how Hamilton pH, DO, and cell density sensor technology helps the Budapest University of Technology and Economics work with different yeast strains to optimize xylitol yield.
App Note - Real-time total cell density measurement of yeast fermentationsDencytee is used to optimize fermentation conditions for yeast processing.
App Note - DO in microbial fermentationF. Hoffmann-La Roche, a Swiss multinational healthcare company, uses optical dissolved oxygen sensors in thier R&D department in Basel to monitor microbial fermentation.
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