SMARTDROP® System

Droplet Measurement
Up to 40 Hz
Analyze individual droplets
Accurate
Volume Calibration
Optimized Control
Advanced
Liquid Characterization
High-Precision Results

Precision Droplet Control

Harness high-speed bright-field imaging combined with intelligent software, SMARTDROP delivers non-contact, real-time volume calibration and droplet validation to deliver precise liquid characterization that supports accurate results across applications.

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Use case

How It's Used

SMARTDROP enables real-time droplet measurement, volume calibration, and liquid characterization for precise, reproducible liquid handling workflows.

SMARTDROP System

High-Speed Droplet Measurement for Liquid Characterization


SMARTDROP captures droplets mid-flight using a high-performance camera with swift shutter speed and adjustable trigger delay. This ensures precise imaging from droplet breakoff to full flight, enabling accurate volume calibration and advanced liquid characterization in automated liquid handling workflows.

Automated, Non-Contact Volume Calibration


SMARTDROP features intelligent software algorithms that automatically calibrate droplet volumes and eliminate satellite formation. The non-contact optical imaging process ensures clean, consistent, and contamination-free dispensing—critical for high-precision workflows in pharmaceutical, diagnostic, and microfluidic applications.

Flexible Integration and Kit Availability


Easily integrated into PIPEJET, SIJET, and Hamilton's automated liquid handling systems, SMARTDROP also supports OEM and custom dispensing setups. For rapid deployment, it’s available as a plug-and-play Kit—ideal for labs and integrators seeking fast setup and reliable real-time droplet validation.

Common applications Manufacturing

Featured Technologies

SMARTDROP captures droplets mid-flight in real time to ensure precision, improve QC, and support consistent volume delivery.

Automated software calibrates droplet volumes, reducing variability and eliminating manual adjustments across different liquids.

Perform mid-run droplet verification during refills or pauses, with logged traceability to ensure uninterrupted quality and consistency.

Visualize and eliminate satellite droplets in real time to ensure clean, accurate dispensing and protect sensitive substrates.

SMARTDROP adapts to Hamilton workstations, standalone setups, or OEM platforms, enabling flexible deployment across diverse workflows.

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Optical Droplet Control

SMARTDROP delivers high-frequency droplet imaging and intelligent volume control, offering scientists precise monitoring, unmatched insight, and control in ultra-low volume workflows. Use it as an add-on or embedded module for consistent and accurate droplet generation.

1

Bright-Field Optical Camera

High-speed camera captures droplets at up to 40 Hz in bright-field mode, visualizing shape and breakoff for real-time droplet validation.
2

Precision Light Source

Aligned LED illumination ensures optimal contrast for droplet imaging, supporting accurate detection of volume and satellite drops.
3

Dispenser Mounting Holder

Securely holds PIPEJET® or SIJET dispensers in the correct alignment for calibration, supporting flexible and repeatable setups.
4

Compact Integration-Ready Design

SMARTDROP’s small footprint fits benchtop use or installs directly into the BIOSPOT® ARC system or custom OEM platforms.
  • SMARTDROP optical imaging module with integrated camera, illumination, and dispenser mount for in-flight droplet calibration.
  • USB stick with pre-installed SMARTDROP control software for droplet setup, visualization, and calibration.
  • Set of five aluminum waste containers included with SMARTDROP Kit for safe liquid disposal during calibration workflows.
  • SMARTDROP Kit includes power and USB cables to connect the module to a PC and control unit for immediate use.

SMARTDROP Kit Components

The SMARTDROP Kit offers a complete plug-and-play setup for evaluating real-time droplet measurement and process control. Ideal for users already working with PIPEJET or SIJET technology, it provides a straightforward way to characterize droplet behavior and validate volume delivery.

1

SMARTDROP Module

Includes high-speed camera, LED light source, and secure dispenser mount for PIPEJET or SIJET. Enables in-flight droplet imaging and non-contact volume calibration on the bench or within a custom dispensing platform.
2

Control Software USB

Plug-and-play USB stick with pre-installed SMARTDROP software. Enables users to configure trigger delay, view droplet images, and optimize dispensing protocols with full parameter control.
3

Waste Containers

Includes five durable aluminum waste containers for clean and efficient liquid disposal during calibration. Reusable and compatible with most benchtop setups.
4

Connectivity Accessories

Includes all required USB and power cables to connect SMARTDROP to a PC and the Control Electronic 200. Ensures reliable setup without needing additional components.
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SMARTDROP System Specifications

SMARTDROP System Specifications

Print

System Dimensions

Height
8.2 cm (3.23 in)
Width
8 cm (3.15 in)
Depth
22 cm (8.66 in)
Complete SMARTDROP system for real-time droplet calibration and in-flight volume monitoring

General Specifications

Weight
0.8 kg

Volume Range 1

up to 100 nL 2

1 Liquid dependent

2 For higher-volume applications, please contact us to discuss custom solutions.

Support your entire workflow with Hamilton's integrated products.

SMARTDROP® enables real-time, non-contact droplet volume verification and calibration without the need for liquid class definitions. Use it as a standalone tool during feasibility testing, then integrate it into BIOSPOT® ARC for automated QC and intelligent calibration directly within your dispensing workflow.

Test. Integrate. Automate.

Start with PIPEJET®, SIJET or SMARTDROP® as standalone tools, then scale up on BIOSPOT® ARC or BIOSPOT®DX for automated dispensing with ready-to-use gantry systems and intuitive workflow software.

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Services
Dispensing Services

Hamilton's Dispensing Service offers feasibility testing to evaluate if your liquid and workflow are compatible with our dispensing technology.

Application and Technical Support

Hamilton's Technical Support team is here to provide product trouble-shooting, repair, application support, virtual start-up support, and more.

Installation Support

Installation, set-up, and calibration support directly on-site. Our field service team ensures your sensors and cables are installed and functioning correctly.

Backed by world-class service and support.

For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.

Let's Talk

Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.

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