OneFerm pH

Hamilton OneFerm single-use pH sensors for biopharma offer reliable, stable measurements with easy integration into SU bioreactors and systems.

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  • OneFerm pH K8 pH sensor

OneFerm pH Details

The Hamilton OneFerm family of pH sensors represents a leading solution for single-use applications within the Pharmaceutical and Biotechnology Industries. These sensors are a significant advancement in single-use measurement, addressing common issues associated with traditional reusable pH sensors inserted into bags. 

Combining the proven reliability and measurement stability of Hamilton's conventional sensors with the convenience of seamless integration into single-use bioreactors, OneFerm sensors offer high accuracy even after gamma irradiation and boast a sufficient shelf life. Their clog-free diaphragm ensures exceptionally low drift throughout the sensor's lifespan, and they can be customized to specific application requirements. 

The OneFerm family is ideal for single-use bioreactors (both bag and rigid container types), single-use mixers, and single-use downstream processes.  

Common applications Pharma & Biopharma, Bioprocess Downstream, Single-Use Bioprocessing, Bioprocess Upstream

Simplified integration of reliable, stable, and accurate pH measurement.

Featuring bio-compatibility, ready-to-use convenience, and a clog-free design.

Market-Leading Single-Use Solution

Recognized as a premier solution for a wide array of single-use applications within the Biopharmaceutical industry.

Ready to Use

Designed for immediate integration and use, simplifying setup and reducing preparation time.

Certified Bio-compatible

Materials used are certified bio-compatible, ensuring suitability for sensitive biopharmaceutical processes.

Clog-free Diaphragm

Clog-free diaphragm ensures extremely low drift during the service life of the sensor.

Scientific Citations

OneFerm pH Specifications

Print
Process Connection PG13,5
Wetted Parts GΙass
VMQ (Silicone elastomer)
Sensor Output Traditional: mV
Measuring Range pH 3 to 10
Sensitivity Before gamma irradiation: 57 to 60 mV/pH at 25 °C (97 % -101 %); Shift after gamma irradiation: ± 1.5 mV/pH
Zero Point Before gamma irradiation: ± 20 mV; Shift after gamma irradiation: ± 10 mV
Calibration Data Yes, provided on sensor label
pH Accuracy After gamma irradiation and dry storage: ± 0.15 pH with provided calibration values.
± 0.1 pH after product calibration at the measurement temperature and within 2 pH units from the product calibration point
Drift at Room Temperature < 0.1 pH per week after wet-in time, in buffer pH 7
Membrane Shape Spherical
Diaphragm HP-Coatramic
O-ring Material FDA 21 CFR 177.2600; EC 1935/2004; USP <87>; USP <88> Class VI (121 °C)
Biocompatibility Yes, tested according to ISO 10993-5 and USP <87>
Wet-in Time 30 min after dry storage
Shelf Life 12 months prior gamma irradiation. 18 months after gamma irradiation
Diameter 12 mm
Autoclavable No
Steam Sterilizable No
CIP No
Gamma Irradiatable Yes, up to 50 kGy
X-Ray irradiatable Yes, up to 50 kGy
Operating Temperature Range 4 to 50 °C
Sample min Conductivity 100 µS/cm

Commonly Grouped Accessories

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OneFerm pH Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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Firmware Updates for Arc Products

Hamilton Arc and VisiFerm ECS sensors rely upon internal firmware for their operation. Periodic firmware updates ensure that the sensor has the latest features and fixes any pre-existing bugs that may exist.
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Article

Working with OneFerm Single-Use pH Sensors

This Knowledge Base article reviews common questions on installation and usage of OneFerm Single-Use pH sensors.
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Article

Bilinear Analog Outputs with Arc Sensors

Bilinear analog (4 to 20mA) outputs are a feature in Arc sensors but are often not well understood. This article provides a brief description of these outputs along with some examples where they can be used.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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FAQ

Does my optical DO sensor require calibration prior to usage?

All Hamilton optical dissolved oxygen sensors come with factory calibration; however, for best accuracy, it is recommended that calibration is performed prior to use. The factory calibration does not account for variations in atmospheric pressure or humidity which are often different based on location.
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FAQ

Where can I find documentation and certificates for my sensors?

Paper copies sensor information such as manuals, declarations of quality, and material certificates ship with the product. Hamilton also has several website resources to find related information. Click on the FAQ to learn more.
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FAQ

How much torque is needed to install a sensor with PG13.5 threads?

Sensors with PG13.5 threads rely on the o-ring to seal against process pressure. Finger-tight (approximately 2 Newton Meter or 18 inch-lb) should be sufficient to install the sensor without leakage. Additional tightening beyond this can deform the o-ring or strip the threads.
Services
Application and Technical Support

Hamilton's Technical Support team is here to provide product trouble-shooting, repair, application support, virtual start-up support, and more.

Modular Service Contracts

Hamilton offers modular service contracts tailored to your requirements, featuring a basic module complemented by optional add-ons.

Installation Support

Installation, set-up, and calibration support directly on-site. Our field service team ensures your sensors and cables are installed and functioning correctly.

Qualification IQ/OQ

Support for the qualification of Hamilton equipment including complete documentation. Readying your process for GMP manufacturing activities.

On-Site Service Diagnostics

Diagnosing and resolution of process system problems on-site. Finding the root cause and presenting a solution to fit your needs.

On-Site Training

User trainings and on-site trainings for technicians. Tailored training ranging from basic operation to advanced calibration and maintenance.

Backed by world-class service and support.

For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.

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