It is challenging to maintain a sterile environment at high throughputs while enabling continuous loading of cells, compound plates and reagents and ensuring data integrity. Automating cell-based assays in high-throughput screening for drug discovery requires special attention to ensure that the system is capable of not only handling the large amount of labware and reagents, but also facilitating continuous loading to keep reagents and cells fresh and avoid evaporation of solvents in compound plates.
Hamilton’s Scheduling Software can be used to interact with the operator and communicate needed replenishments. The Autoload feature allows the operator to load reagents, plates and other supplies while the system is active without getting in the way of moving parts. In addition, all compounds and their dilutions can be traced through the process until the final result.