Incyte-P SU

Part # 10076676

Hamilton Incyte-P SU sensor element provides a cost-effective, viable cell density measurement solution for integration into single-use containers. It offers a perfect balance between high reliability and affordability, utilizing proven sensor technology from traditional sensors.

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Incyte-P SU Details

The Hamilton Incyte SU family of Viable Cell Density (VCD) sensor elements offers a leading solution for single-use applications in the Pharmaceutical and Biotechnology industries. These sensors represent a significant advancement in single-use measurement, addressing common issues associated with traditional reusable VCD sensors inserted into bags or benchtop bioreactors. They combine the proven reliability and measurement stability of Hamilton's conventional sensors with the convenience of seamless integration into single-use bioreactors.  

The Incyte SU sensor elements provide high accuracy even after gamma irradiation and have a sufficient shelf life. The Incyte SU family is ideal for single-use bioreactor bags. The difference between the Incyte-P SU and the Incyte-PO SU lies in their compatibility with various bioreactor bag films available on the market.  The Incyte SU sensors, combined with the Arc Module Incyte SU, provide industry-standard digital Modbus RTU signals. An analog signal (4 to 20 mA) is also available with an Arc Wi 2G adapter BT.

The Incyte SU sensor is designed for measuring viable cells during mammalian cell culture, yeast, and high-density bacterial fermentation. The measurement principle of Incyte sensors is based on permittivity, where viable cells behave like capacitors.  Their polarization and depolarization in an alternating electrical field are measured, correlating to viable cell density and remaining insensitive to cell debris and microcarriers.

Common applications Pharma & Biopharma, Bioprocess Downstream, Single-Use Bioprocessing, Bioprocess Upstream, Biotechnology

Gain deeper process insights.

Real-time viable cell density measurement.

Description: Ready-to-use and pre-calibrated patches.

  • The difference in measurement resolution between the off-line method and permittivity is like between a 60's TV and an 8K screen!

    We used the Incyte Arc Sensor to monitor the viable cell density. It is very easy to install in a bioreactor and connect to the monitoring software. After performing a baseline calibration in medium, you are ready to monitor your bioreactor run.

    Jort Altenburg, Ph.D
    Wageningen University, Netherlands

Incyte-P SU Specifications

Print
Wetted Parts Platinum
Ceramic / Glass
HDPE (High Density Polyethylene)
See compliance details in Material Specification document
Parameter Viable Cell Density
Measuring Range 0 to 700 pF/cm, equivalent to 5 x 10^5 to 8 x 10^9 cells/mL (mammalian)
Calibration Data Yes, provided on sensor label
Temperature Sensor Yes
Biocompatibility Yes, see separate study report (upon request)
Wet-in Time 30 min after dry storage
Shelf Life 12 months prior gamma irradiation
24 months after gamma irradiation
Serial Number No
Certificate Yes
Autoclavable No
Steam Sterilizable No
CIP No
Gamma Irradiatable Yes, up to 50 kGy
X-Ray irradiatable Yes, up to 50 kGy
Operating Temperature Range 4 to 50 °C
Conductivity Range 1 to 50 mS/cm
Pressure Range bar g 0 to 1 bar
pH Range 3 to 10
Patch type Legacy

Incyte-P SU Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Laptop displaying bioprocess VCD model validation charts with residual plots and observed vs. predicted curves

Article

ArcAir Data Modeling Software

VCD Soft Sensor: Close the gap between your off-line viable cell density data points.
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Article

Firmware Updates for Arc Products

Hamilton Arc and VisiFerm ECS sensors rely upon internal firmware for their operation. Periodic firmware updates ensure that the sensor has the latest features and fixes any pre-existing bugs that may exist.
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Article

Incyte Cell Density Measurement Principles

Incyte enables the dual frequency measurement mode, or a frequency scanning. Learn about how Hamilton Incyte cell density sensors can continuously measure viable cells.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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FAQ

Can the electric field of Incyte damage/harm the cells?

No. The frequency of the electric field applied by the system is within 300 kHz and 10 MHz. These frequencies do not damage the cells.
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FAQ

How does Incyte measure viable cell density?

Incyte is a capacitance-based sensor responsive only to living cells.
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FAQ

Will Incyte work with my cell line?

Incyte has been shown to work with cell lines ranging from cell culture to microbial fermentation. We have compiled a current list of known applications in our cell density applications ebook. Download a copy to learn more.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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Webinar

Total Cell Density Reimagined

In this webinar we introduce Hamilton's Dencytee Arc sensor and the measurement principles guiding it's development. Measurement by the Dencytee sensor is based on optical density and can be correlated to different offline measurement techniques.
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Support for the qualification of Hamilton equipment including complete documentation. Readying your process for GMP manufacturing activities.

Maintenance and Calibration Services

Preventative maintenance and regular service contracts. Schedule on-site service dates to ensure your sensors are properly maintained and your process is optimized.

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Diagnosing and resolution of process system problems on-site. Finding the root cause and presenting a solution to fit your needs.

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User trainings and on-site trainings for technicians. Tailored training ranging from basic operation to advanced calibration and maintenance.

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Installation, set-up, and calibration support directly on-site. Our field service team ensures your sensors and cables are installed and functioning correctly.

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