Application

Cultivated Fish and Seafood

Cultivated seafood is a growing area in food innovation, offering sustainable alternatives to traditional seafood products. This approach uses cultivated cells from marine animals. The process relies on providing the seafood cells with molecular and environmental cues during growth and development. It is an immensely promising approach for alleviating pressure on both wild fisheries and aquaculture systems. 

Accelerating the development and widespread commercialisation of cultivated seafood can aid global strategies to maintain ocean vitality and survival.

Cultivated fish and seafood production
fishes in ocean
bioprocessing bioreactor

This innovative bioprocessing approach addresses challenges of traditional seafood production by offering fundamentally higher efficiencies compared to conventional methods. Caloric energy loss through the wild food chain is eliminated, as is the wasteful production of low-value bioproducts, such as bones. Furthermore, producing cultivated seafood in aseptic cultivators improves shelf life and reduces contamination risks. 

Advancing this field requires substantial research and development, particularly the development of tools and resources for aquatic species cell culture.

How Hamilton Supports Your Lab-Grown Seafood Process Workflow

Hamilton partners with researchers to advance cultivated seafood production through specialized tools and bioprocessing support for aquatic cell lines. Our advanced sensor technologies streamline workflows from media preparation to harvest, ensuring precise control of critical parameters to support scale-up, consistency, and regulatory compliance.

Learn more about our solutions along the cultivated fish and seafood workflow:

The preparation of cell culture media in prep tanks requires pH and conductivity monitoring. This ensures cell viability, avoids nutrient depletion, and supports cell viability under optimal nutrient conditions. 

During this upstream process, seed trains expand primary cells in preparation for the primary bioreactor. Precise control of pH, DO, DCO2, and cell density is vital for robust cell growth and maximizing product yield. 

Upon reaching optimal density, proliferated cells undergo differentiation, mirroring conventional fish and seafood. This maturation process is guided by specific media components and, often, scaffolds.

Harvesting occurs when cells reach optimal density, with ongoing parameter measurement ensuring enhanced control and improved yield. This step supports consistent production process efficiency.

 Reusing media and water can lower process costs without compromising quality. Accurate pH and conductivity control are essential for supporting cell growth in recycled culture media. Wastewater pH monitoring is necessary for regulatory standards.

Explore Our Solutions for Cultivated Fish and Seafood Applications in Detail

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Incyte Arc Expert sensors enable real-time, in-situ measurement of viable cells, making it possible to detect events and respond in real time without increased off-line sampling.
The Hamilton’s Incyte SU sensor elements are pre-installed as integral part of the single-use container with a long shelf life.
Dencytee Arc RS485 sensors enable real-time, in-situ measurement of total cell density using transmittance and reflectance of near-infrared light in low and high cell density applications. Reduce off-line sampling and increase the reliable optical density measurement range.
EasyFerm Bio pH sensors offer Foodlyte biocompatible electrolyte and EHEDG Certification for pH measurement in processes where non-toxicity is mandatory.
Hamilton EasyFerm Plus pH sensors are the most popular product for pharmaceutical applications where autoclave and SIP are frequently performed. They provide accurate and stable pH measurement in demanding biopharma processes.

VisiFerm Dissolved Oxygen Sensors

VisiFerm RS485-ECS

VisiFerm RS485-ECS is an advanced optical dissolved oxygen sensor for biotechnology, biopharmaceutical, and food and beverage industries, offering full measurement functionality, self-diagnostics, and simplified maintenance.

VisiFerm Dissolved Oxygen Sensors

VisiFerm mA

Less frequent calibration and longer lifetime. 2-wire 4-20mA / HART for GMP production environments. Explosive-rated environments.

Arc Module and VisiFerm SU

VisiFerm SU RS485-ECS

The VisiFerm SU RS485-ECS is designed for reliable dissolved oxygen (DO) measurement in single-use applications with the ODO Cap Sx sensor element.
VisiWater sensors are optical technology sensors intended for the measurement of dissolved oxygen submersible applications in the environmental water industry.

Conductivity Sensors

Conducell 4UxF

Great linearity over a broad measurement range. Well suited for hygienic applications with standard PG13.5 threads as well as Varivent and Neumo BIOConnect options.

Lab Syringes

Gastight Syringes

The solution for dispensing both gases and heterogeneous liquids. Hamilton Gastight syringes are equipped with a precision-machined PTFE plunger tip to create a leak-free seal.
Hamilton Microliter syringes are ideal for dispensing homogeneous liquid samples not prone to glass bonding or precipitation. With a hand-fitted stainless steel plunger for frictionless movement and minimal wear, these syringes are designed to last.

Hamilton Conductivity and pH Sensors for Media Preparation

Discover our sensor solutions for monitoring conductivity and pH in cell culture media preparation tanks. Save costs by producing media on-site. Hamilton conductivity and pH sensors ensure the media's continuity and reproducibility. By utilizing these advanced sensor technologies, you can optimize your media preparation process, improve downstream bioprocessing efficiency, and ensure consistent, high-quality cultivated meat products. 

Learn more about our Conducell 4USF Arc Conductivity Sensor and our EasyFerm Bio pH Sensor. Talk with our experts to learn how our single-use sensors can improve your media preparation and upstream bioprocessing workflows.

Solutions for Top 3 Challenges in Cultivated Fish and Seafood

Maintaining Optimal Cell Growth Conditions for Faster and Healthier Cell Development

Solution: Hamilton Sensor Technologies precisely controls DCO2, DO, and pH, enabling ideal conditions for accelerated and enhanced cell growth. 

Maximising Yields During the Bioprocess Stage 

Hamilton Incyte and Dencytee sensors directly measure viable and total cell density in-line and in real-time, helping users to determine the optimal time of harvest. 

Achieving Consistent and Scalable Bioprocess Production

Solution: Hamilton process analytical technologies facilitate seamless process scale-up and improve batch-to-batch reproducibility, ensuring stable and consistent production.

Cultivated Fish & Seafood Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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