AutoLys STAR
Consistent, Automated
Tube-in-Tube Assembly
Lysis and DNA Extraction
Reduce Backlogs
Up to 96
Samples Per Run
Optimized Process
High DNA Yield
Fully Enclosed System
Highly Reproducible DNA Sample Prep Workflow
From sample input to lysate recovery, AutoLys STAR delivers reproducible, secure forensic DNA extraction along with full sample traceability.
Scientific Citations
Automated Cell Lysis and DNA Extraction System
The AutoLys STAR Assay Ready Workstation fully automates sample lysis and lysate recovery. It integrates incubation, shaking, and centrifugation steps along with barcode tracking in a closed-loop system.
AutoLys STAR works with Hamilton’s AutoLys Tubes featuring an inner tube with filter to hold the sample and an outer 2D-barcoded tube to collect post-centrifugation sample lysate. On the deck, AutoLys channels securely cap, decap, and transport the AutoLys Tubes.
As an ideal solution for forensic and diagnostic laboratories, AutoLys STAR enables high-throughput processing to reduce backlogs and sample processing errors for increased confidence in downstream results.
Automated Differential Extraction
Use AutoLys STAR to automate complex differential extraction steps based on the Gill method. Hands-free processing reduces analyst time and risks of variability.
Secure Chain-of-Custody
When the AutoLys tube barcode is scanned on the AutoLys STAR, information is sent to a LIMS to enable a fully traceable digital audit trail. Detailed run files may be downloaded and standardized to include in case files.
Common applications Genomics, Nucleic Acid Extraction, Biobanking, Pharma & Biopharma, Drug Discovery
Featured Technologies
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Transport SolutionsCO-RE Gripper
For Additional Movements
Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.
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Pipetting TechnologyCO-RE II Tip/Tool Attachment
The Key to Liquid Handling Workflow Excellence
The new CO-RE II technology assures more precise tip alignment, minimizing the risk of collisions. Also, tip coupling is faster which boosts productivity. Besides tips, a wide range of Hamilton tools are applicable with CO-RE II.
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Pipetting TechnologyAerosol-Free Tip Ejection
To Prevent Cross-Contamination
As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.
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Liquid Handling TechnologyMAD - Monitored Air Displacement
For Unmatched Reliability
MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.
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Liquid Handling TechnologyDual Liquid Level Detection (LLD)
For Accurate Aspirations
Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.
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Liquid Handling TechnologyTADM – Total Aspiration & Dispense Monitoring
For Real-Time Pipetting Accuracy
During aspirate and dispense steps, TADM monitors real-time pressure changes in each Hamilton liquid handler pipetting channel. Results are compared against expected values to expose anomalies like bubbles and insufficient volumes. Sample transfers are verified with a digital audit trail.
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AccessoriesAutoload
For Convenient Identification
Uses a 1D barcode scanner to automatically identify and verify samples, carriers, and consumables such as tips, tubes, micro plates, and reagent troughs as they are placed onto the liquid handling deck. Optional 2D barcode reading is available, and results may be sent to any LIMS for documentation.
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Liquid Handling TechnologyAnti-Droplet Control (ADC)
For Drip-Free Pipetting
Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.
Fully automated sample lysis and lysate recovery reduce risks of human error and variable manual handling to improve process safety and reliability.
Enhanced heating and shaking design boosts sample lysis efficiency, delivering significantly higher yields for low-input samples compared to manual methods.
AutoLys STAR scans 2D barcodes on the AutoLys tubes for detailed end-to-end sample tracking required by regulated and forensic laboratories.
Easily process up to 96 samples per run with flexible AutoLys STAR configuration options to adapt to diverse application formats and volumes.
Explore the AutoLys STAR
The AutoLys STAR automates the full sample lysis process—from sample input to lysate recovery. Optimized for traceability, yield, and reliability, this integrated system combines Hamilton’s engineering with forensic-grade quality to meet the demands of regulated labs and high-throughput facilities.
1
Microlab STAR
The Microlab STAR automated liquid handler performs all pipetting steps and houses on-deck devices necessary for other workflow steps.
2
AutoLys Channels
These channels independently manage critical AutoLys tube handling steps, including automated capping, decapping, and ‘lift-and-lock' positioning.
3
AutoLys Tubes (Sold Separately)
AutoLys Tubes, sold separately, feature a tube-in-tube design that separates sample lysate via filtration to eliminate manual transfers.
4
Heater Shaker Module
Hamilton Heater Shakers include custom adapters to secure AutoLys tubes, ensuring optimal heat transfer and consistent mixing.
5
Integrated Centrifuge
The compact swing-out centrifuge automates lysate filtration with seamless robotic integration, delivering efficient and fully hands-free sample processing.
6
EasyCode Barcode Reader
This high-resolution reader scans AutoLys tube 2D barcodes to support complete traceability and chain of custody documentation throughout the workflow.
AutoLys STAR Specifications
AutoLys STAR Specifications
PrintSystem Dimensions
- Height
- 90.3 cm (2 ft, 11.55 in)
- Width
- 1.66 m (5 ft, 5.35 in)
- Depth
- 78.1 cm (2 ft, 6.75 in)
Transport Tools
- CO-RE Gripper
- Standard
Platform/Accessories
- Capacity (ANSI/SLAS Positions)
- 55
- Device Integration
- 180° (Left and Right)
Sample Loading and Tracking Options
- Sample Loading
- Automatic
- Autoload Barcode Scanner (1D)
- Standard
- Autoload Barcode Scanner (2D)
- Optional
Pipetting Options
- 1 mL Channels
- 4
- AutoLys Channels
- 4
- Pipetting Range 1
- 1 µL - 1000 µL
1 Depending on Configuration
AutoLys STAR Resources
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Services
Trust in Hamilton’s Field Service Engineers for high-quality automated liquid handler installation, preventative maintenance, and field repairs.
Backed by world-class service and support.
For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.
Let's Talk
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