General Syringes

Microliter Syringes

Gas Tight Syringes
Microliter vs. Gastight Syringes
Microliter Syringes For Liquids
Microliter syringes incorporate a hand-fitted stainless steel plunger with a finely bored syringe barrel. These syringes are ideal for organic samples that are not prone to precipitation, crystallization or bonding with glass.
Under the proper conditions, plunger wear is minimal and the life of a Microliter syringe is almost unlimited. However, when using heterogeneous solutions with a Microliter syringe, the user must be especially diligent about cleaning the syringe after each use. In some cases, even diligent cleaning is not sufficient and the barrel will become soiled. The deposits on the glass will compromise the tight tolerances between the glass and the plunger resulting in a frozen plunger. Plungers for Microliter syringes cannot be interchanged or replaced if damaged.
For aqueous and low volatile solutions, a Gastight syringe is the best option.
Gastight Syringes For Liquids and Gases
Gastight syringes have a precision-machined polymer plunger tip, often PTFE, which creates a leak-free seal. With the tight fit, the tip essentially wipes the interior of the syringe barrel free of sample. This feature is particularly useful with aqueous and low volatile organic samples because it reduces the chance that a deposit will occur and cause the plunger to freeze.
The Gastight series still requires careful and regular cleaning to minimize deposits on the glass which might score the soft PTFE plunger tip and result in a leak. Replacement plunger assemblies are available for Gastight syringes. However, a replacement plunger should not be put into a barrel that still contains deposits because the new plunger tip is likely to be scored by the deposit after only a few strokes. It is important to remember that over time, the increased friction created by the tight seal may cause the PTFE tip to wear out and the plunger will have to be replaced.
Anatomy of a syringe

Additional Pages and Resources for Hamilton Laboratory Products
Check out our page for Hamilton Laboratory Products
See the complete line of Hamilton Chemistry Syringes here.
Resources
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Reference Guide - Laboratory Syringes and Needles
The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips. -
Syringe Care and Use Guide
Hamilton’s Syringe Care and Use guide outlines the basics of daily syringe use and operation so that scientists and technicians can achieve the highest level of accuracy and precision. Important topics covered include inspection, operating temperature, trapped air, and sample carryover. -
Instructions - Hamilton SaltLine Syringes
SaltLine syringes were developed to combat the rigors of solutions with high salt concentrations.
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What does the s mean in a 22s or 26s gauge needle?
The "s" represents a smaller inner diameter for the needle and a thicker needle wall for better durability. For example, a 26 gauge needle has an outer diameter of 0.46 mm and an inner diameter of 0.26 mm while the 26s gauge needle has an outer diameter of 0.47 mm and an inner diameter of 0.13 mm. The 26s has half the inner diameter of the 26 gauge needle. The difference in the wall thickness also nearly doubled with 26s gauge having a thickness of 0.18 mm while the 26 gauge is only 0.10 mm. -
I have a syringe, which needle do I need?
If you already have a syringe and need a Hamilton needle, you can determine the appropriate needle if you know one of the following: 1) the glass syringe termination; 2) the glass syringe part number; or whether you are dealing with a common plastic syringe. Click the heading to learn more. -
What is the accuracy of Hamilton syringes?
Hamilton syringes are manufactured to be accurate within ±1% of nominal volume, and with precision within 1%, measured at 80% of total scale volume. The design of our barrel and plunger dimensions assures high levels of accuracy and precision. The Hamilton Company Quality System is ISO 9001: 2015 certified.
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Syringe Dimensions
See the specific volumes, outer diameter measurements, and inner diameter measurements of all microliter syringes. -
Syringe Sterilization and Disinfecting Guide
Are you curious whether your Hamilton syringe can be sterilized and disinfected via ethylene oxide, autoclavation, or chemical disinfectants? Consult this table of syringe terminations, syringe needles, and tubing types to learn the possible ways to sterilize and disinfect you Hamilton syringe. -
Syringe Terminations
One of the first steps to understanding the ideal syringe for your specific application is to know which termination is best. This article helps you make that determination, explaining what to choose based on your requirements like dispense volume, need for autoclaving, desired dead volume, pressure tolerances, or necessary headspace.

Work with R&D engineers to customize Hamilton parts
Hamilton's "Custom Built" program puts you directly in contact with a Hamilton R&D Engineer to discuss your application and product needs. The engineer will point you to a standard solution or propose a customized solution to meet your needs.
Talk to an engineer