Syringe Microliter Cemented Needle

Microliter Syringes

Hand-fitted stainless steel plungers achieve a liquid-tight seal with a nearly frictionless operation, minimizing wear and ensuring longevity.
Gas Tight Syringe Luer Lock

Gas Tight Syringes

Inert PTFE plunger tips create a gastight seal that is ideal for long dispense times, heterogenous solutions, or viscous liquids.

Microliter vs. Gastight Syringes

Microliter Syringes For Liquids

Microliter syringes incorporate a hand-fitted stainless steel plunger with a finely bored syringe barrel. These syringes are ideal for organic samples that are not prone to precipitation, crystallization or bonding with glass.

Under the proper conditions, plunger wear is minimal and the life of a Microliter syringe is almost unlimited. However, when using heterogeneous solutions with a Microliter syringe, the user must be especially diligent about cleaning the syringe after each use. In some cases, even diligent cleaning is not sufficient and the barrel will become soiled. The deposits on the glass will compromise the tight tolerances between the glass and the plunger resulting in a frozen plunger. Plungers for Microliter syringes cannot be interchanged or replaced if damaged.

For aqueous and low volatile solutions, a Gastight syringe is the best option.

Gastight Syringes For Liquids and Gases

Gastight syringes have a precision-machined polymer plunger tip, often PTFE, which creates a leak-free seal. With the tight fit, the tip essentially wipes the interior of the syringe barrel free of sample. This feature is particularly useful with aqueous and low volatile organic samples because it reduces the chance that a deposit will occur and cause the plunger to freeze.

The Gastight series still requires careful and regular cleaning to minimize deposits on the glass which might score the soft PTFE plunger tip and result in a leak. Replacement plunger assemblies are available for Gastight syringes. However, a replacement plunger should not be put into a barrel that still contains deposits because the new plunger tip is likely to be scored by the deposit after only a few strokes. It is important to remember that over time, the increased friction created by the tight seal may cause the PTFE tip to wear out and the plunger will have to be replaced.

Anatomy of a syringe

Syringe Microliter Gastight

Additional Pages and Resources for Hamilton Laboratory Products

Check out our page for Hamilton Laboratory Products
See the complete line of Hamilton Chemistry Syringes here.


Hamilton's knowledge base provides a range of explanatory articles, frequently asked questions, and document downloads.
  • Reference Guide - Laboratory Syringes and Needles

    The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
  • Syringe Care and Use Guide

    Hamilton’s Syringe Care and Use guide outlines the basics of daily syringe use and operation so that scientists and technicians can achieve the highest level of accuracy and precision. Important topics covered include inspection, operating temperature, trapped air, and sample carryover.
  • Instructions - Hamilton SaltLine Syringes

    SaltLine syringes were developed to combat the rigors of solutions with high salt concentrations.
Syringe Custom Built

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