PRP-X600: Methacrylate (WAX) Anion Exchange HPLC Column

Hamilton's PRP-X600 HPLC Column

PRP-X600 is a superficially porous weak-base anion exchange support that separates DNA oligomers according to negative charge. The unique porosity provides fast separation with better sample capacity than non-porous supports. The superficially porous properties shorten the diffusion path of the analyte, resulting in sharp sample bands. The PRP-X600, a hydrophilic methacrylate-based polymer, improves sample recovery due to minimized hydrophobic interactions.


Application Examples: Nucleic acids such as single-stranded/double-stranded RNA and DNA, peptides, and proteins.

 

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PRP-X600 Columns

PRP-X600 columns give fast separations with better sample capacity for biomolecules.
Anion card

PRP-X600 Guard Columns

Protect your PRP-X600 column.
Guard columns

PRP-X600 Bulk Resin

Pack your own column.
Bulk resin

Tech Center

HPLC Column Care & Troubleshooting
HPLC Resin Specifications
HPLC Guard Cartridge Holder Assembly - PEEK
Safety Data Sheets
Choosing Column Specifications

PRP-X600: Methacrylate (WAX) Anion Exchange HPLC Column Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

HAM Reference Guide HPLC Columns

Guide

Reference Guide - HPLC Columns

Learn how to choose a column, how to maximize the life of a column through proper care, cleaning, and restoration.
HAM SDS PRP X600 resin dry

SDS

SDS - PRP-X600 (resin, dry)

Download the Safety Data Sheet for Hamilton PRP-X600 Resin (Dry), used as a filter media in HPLC applications. Includes key safety, handling, and first aid information.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

cation exchange column

Article

USP "L" Column Listings

Explore Hamilton’s qualifying USP “L” columns.
Anion columns

Article

PRP-X600 Anion Exchange DNA Column

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

HPLC FAQ

FAQ

How do I restore my HPLC column?

Performance will inevitably degrade as the column is used, however this procedure may restore the performance of a column that has become fouled. Learn more in this step-by-step guide.
HPLC FAQ

FAQ

How Do I Connect a Stainless Steel Guard Cartridge to my HPLC Column?

The process of connecting a guard cartridge to an HPLC column is fairly simple, but requires different steps based on the HPLC instrument and the guard cartridge configuration. Click to read our step-by-step guide.
HPLC FAQ

FAQ

How Do I Connect a Stainless Steel Guard Column to My HPLC Column?

Connecting a guard column to an HPLC column is straightforward, but requires different steps based on the HPLC instrument and its configuration. Click the headline above to read this step-by-step guide.
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