Using Design-of-Experiments (DoE) and automation for cell culture optimization

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In this video, we show how to leverage Synthace’s DoA and Hamilton’s automated liquid handlers to optimize the expression of a fluorescent-tagged protein of interest in neural stem cells. Learn how:

  • Synthace’s DoE software allows parallel testing of 128 different combinations of growth factors
  • The use of Hamilton’s 96 Multi-Probe Head and the integration of a plate washer and plate reader to the liquid handler increases throughput
  • The use of Hamilton’s CO-RE pipetting technology and VENUS flexible pipetting parameters allows gentle and precise handling of cells
  • The results can be immediately analyzed on Synthace’s platform, and the next DoE test can be easily set up.

Powerful software, powerful technology, efficient experiments, faster results.