Assessing the Efficacy of Vaccines through Laboratory Assays
Vaccine Research
What’s in the eBook
Several methods and platforms have been developed over the years to produce vaccines—ranging from live-attenuated forms of the pathogen to recombinant RNA vaccines.
Regardless of the type of vaccine, the endpoints used to measure their efficacy are the same: prevention from infection, transmission, disease, and death. Most of the laboratory tests used by clinicians to measure the occurrence of current and past infection and the levels and types of immunogenicity can be automated.
Automation-friendly assays include Enzyme-Linked Immunosorbent Assays (ELISA), flow cytometry, neutralization assays, and quantitative PCR (qPCR).
Read the full eBook to learn more.