Automating ELISA-based Assays to Assess the Purity of Therapeutic Viral Vectors

Cover image for Hamilton case study on AGC laboratory process optimization

What’s in the Case Study

In this Case Study, the Analytical Development group at AGC Biologics Milan describes the automation of two ELISA-based workflows to assess lentiviral vector purity, using a Hamilton Microlab® STARlet liquid handler integrated with a plate washer, a plate spectrometer, and two plate incubators.

Highlights of this Case Study

  • Overview of the analytical methods automated by AGC Biologics Milan on Hamilton liquid handlers
  • Detailed description of two ELISA-based automated workflows to assess the purity of the lentiviral vectors: residual benzonase and residual Host-Cell Proteins (HCP)
  • Advantages of the Hamilton VENUS Scheduler to plan and execute parallel assays using the same sample aliquot

Read the full Case Study to learn more.