Automated Handling of Easily Detachable HEK293 Cells with Cell Care STAR: Improving the Cultivation of Fragile Cell Lines

Gentle Automation for Sensitive HEK293 Cell Culture

Automating sensitive adherent cell workflows requires precise, reproducible handling. This application note demonstrates how the Cell Care STAR enables reliable cultivation, media exchange, expansion, and seeding of easily detachable HEK293 cells using its dedicated “Sensitive Cells” mode. Column-wise processing minimizes mechanical stress, preserves monolayer integrity, and reduces operator-dependent variability.

• Reduced handling variability: Automated column-by-column processing maintains intact HEK293 monolayers during media exchange.
• Consistent cell distribution: Controlled expansion and seeding workflows deliver low inter-plate variability and reproducible confluency.
• Minimized cross-contamination: Individual column-based handling supports parallel cultivation of multiple clonal lines.

Read the full Application Note to learn more.