Automating Cell Line Development with Cell Care STAR: End-to-End Lentiviral Transduction, Selection, and Expansion

Hamilton application note cover: "Automating Cell Line Development with Cell Care STAR" showing workflow diagram for lentiviral transduction, selection, and expansion.

End-to-End Automation for Lentiviral Cell Line Development

Stable cell line development is essential for bioproduction and biomedical research—but traditional workflows remain manual, variable, and time-intensive. This application note demonstrates how the Cell Care STAR enables fully automated, end-to-end lentiviral transduction, antibiotic selection, and expansion. By integrating precise serial dilutions, controlled medium removal, and long-term culture scheduling, the system delivers a reproducible, walk-away workflow for stable cell line establishment.

  • Enhanced biosafety: Minimizes manual interaction during lentiviral transduction and drug selection.
  • Precise serial dilution: Automated preparation of viral vectors and antibiotics ensures accurate titration and kill curve determination.
  • Reproducible expansion: Long-term, hands-off culture and selection accelerate stable cell line generation with full traceability.

Read the Full Application Note to Learn More.