Reducing Variability and Hands-On Time in Clinical Proteomics with Automated SP3 Digestion and Evotip Loading on the Microlab® STAR™

Application note cover: Hamilton and CECAD logos, title on automated SP3 digestion and Evotip loading on Microlab STAR

Scale Clinical Proteomics with Automated SP3 Digestion and Evotip Loading

High-throughput clinical proteomics requires sample preparation that keeps pace with modern LC-MS. This application note demonstrates automated sample lysis, SP3 digestion, and Evotip loading on the Microlab® STAR™, reducing variability and hands-on time for large clinical cohorts.

Key Takeaways

  • Reduced variability: Automation reduced in-batch and batch-to-batch variance by almost 50% compared with manual preparation.
  • Less hands-on time: Automated processing reduced hands-on time by more than 70%.
  • Higher throughput: 96-well plate processing helps align sample preparation with modern mass spectrometry throughput.

Read the Full Application Note to Learn More.