Automated extraction of HMW DNA with PacBio® Nanobind® on the NIMBUS® Presto ARW
Rapidly emerging long-read sequencing technologies, including PacBio Single Molecule, Real-Time (SMRT®) sequencing, provide substantial advantages for (de novo) genome assembly, detecting structural variants, and higher accuracy in repetitive or high GC content regions. A key requirement for long-read, third-generation sequencing approaches is the extraction of HMW DNA (50 kb – 250 kb).
As the field matures and sample numbers increase, robust, high-throughput sample preparation methods are needed to support large-scale studies in pan-genomics and clinical research applications.
Download the Application Note to learn more.