NGS STAR

The Premiere Solution for NGS
The NGS STAR assay-ready workstation is a comprehensive solution for next-generation sequencing (NGS) applications from whole genome to whole transcriptome sequencing and targeted sequencing applications.
The fully automated library preparation system can be customized for use with assay chemistries from leading industry partners, processing 96 libraries at once.
Features and Benefits of the NGS STAR

Fully Optimized NGS Solution
The NGS STAR is an affordable and versatile system that delivers substantial value to our customers. The NGS library prep workflows we developed with industry-leading partners, including:
- Illumina
- Integrated DNA Technologies - IDT
- New England BioLabs
- Oxford Nanopore Technologies
- Pacific Biosciences
- QIAGEN
- Roche KAPA
- Thermo Fisher Scientific
- Twist Biosciences
Have specific questions, or don’t see a desired provider on this list? Contact our dedicated application experts, who will provide
high quality guidance and translate specific needs into reliable and efficient automated workflows.

Individualized Flexibility
The NGS STAR uses an open deck layout so that every system is fine-tuned to the lab’s specific NGS workflow, throughput, and assay needs. At the same time, the system is easily updated to keep pace with protocol updates, or as requirements evolve over time. Our customers can also choose from a wide range of options to customize their system. The NGS STAR is available as an open or enclosed solution, with a variety of cooling and airflow configurations.

Precise, Repeatable Liquid Handling
Air displacement pipetting using Hamilton tips with CO-RE (Compressed O-Ring Expansion) technology provides superior measurement accuracy, precision, and reproducibility without tip distortion or aerosol generation during tip pick-up and ejection.

Hands-Free, Hassle-Free Operation
As a fully automated system, NGS STAR significantly reduces the number of cumbersome preparation steps required by current methods during runs of 1 to 96 samples. User-friendly software guides operators through the automated process, and automated barcode verification ensures proper placement of samples, reagents, plates, and tips. Each step in the aspirate and dispense process is continuously monitored for accuracy so that your lab can remain confident about getting consistent results throughout its operation.
Specifications
All specifications are based on the Microlab STAR.
Dimensions | |
---|---|
Length | 31.2 in (795 mm) |
Width | 65.6 in (1664 mm) |
Height | 35.6 in (903 mm) |
Biologically Tested Methods for NGS STAR
Elevate NGS Precision with Biologically Tested Methods
Experience the pinnacle of Next-Generation Sequencing (NGS) precision. Our NGS STAR platform is engineered for discerning laboratory experts, offering biologically tested methods.
With our rigorous validation processes, you can expect:
Scientific Excellence: Collaborative development with industry experts ensures the highest scientific standards.
Unwavering Reproducibility: Achieve consistent, reliable results, eliminating variability.
Efficient Workflows: Streamlined NGS processes let you focus on your clinical research.
Discover biologically tested methods that redefine precision with NGS STAR.
Ready to enhance your NGS research? Contact us for details.
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Targeted Enrichment for NGS Automation
Do you find traditional, laborious DNA sequencing methods inefficient and unreliable? Targeted enrichment is a revolutionary technique that makes it possible to isolate specific regions of the genome for more accurate sequencing results. Our targeted enrichment methods utilize cutting-edge technology to provide you with high-quality results, saving you time, money, and resources. Say goodbye to traditional shotgun sequencing and hello to targeted enrichment - the future of genetic analysis.
Check out some of the targeted enrichment methods we offer:
Targeted Enrichment Whole Genome Sequencing Agilent SureSelect XT HS2 (DNA and RNA System)
Agilent SureSelect XT Low Input Dual Index
IDT xGen enrichment for Illumina (Exome Research Panel)
Illumina AmpliSeq Custom Panels
Illumina COVIDSeq Illumina TruSeq DNA PCR-Free
Illumina DNA Prep with Enrichment (Exome)
Illumina TruSeq RNA Exome
Illumina TruSight Oncology 500
Illumina TruSight Oncology 500 HT
Illumina TruSight RNA Fusion
Illumina TruSight Tumor 170
Ilumina 16S rRNA Seq NEBNext ARTIC SARS-CoV-2 FS Library Prep
Oxford Nanopore PCR tiling (SARS-CoV-2, ARTIC protocol)
Oxford Nanopore PCR tiling of SARS-CoV-2 ('Midnight Kit' version)
PacBio Whole Genome and metagenome libraries using SMRTbell prep kit 3.0 Transcriptome Sequencing
Paragon Genomics CleanPlex-SARS-CoV-2-Flex-Panel
QIAGEN QIAseq DIRECT SARS-CoV-2 Kit
QIAGEN QIAseq Multimodal Panel
QIAGEN QIAseq Multimodal Panel HT
QIAGEN QIAseq SARS-CoV-2 Primer Panel & Qiagen QIAseq FX DNA
QIAGEN QIAseq Targeted DNA Panel (multiple panels)
QIAGEN QIAseq Targeted DNA Pro Panels
Roche Avenio Tumor Tissue CGP Kit
Roche KAPA HyperCap Workflow v3.0
Twist Bioscience Human Core Exome
Twist Bioscience SARS-CoV-2 Research Panel
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Whole Genome Sequencing
Are you searching for a way to gain a complete understanding of an organism's genetic blueprint? With our state-of-the-art sequencing technologies and methodologies, we can analyze an organism's entire genome to provide an unprecedented amount of detailed genetic information.
We work with you to customize the sequencing process by tailoring it to meet your unique research goals—from sample preparation to data analysis. We utilize a variety of methods and technologies, including:
Whole Genome Sequencing
Illumina TruSeq Nano DNA
Illumina Nextera XT
Illumina DNA Prep
Illumina DNA PCR-Free Prep
NEBNext Ultra II DNA Library Prep
NEBNext Enzymatic Methyl-Seq
Oxford Nanopore Genomic DNA by Ligation (SQK-LSK109-XL)
Oxford Nanopore Genomic DNA by Ligation (SQK-LSK114-XL)
Perkin Elmer NEXTFLEX Cell Free DNA-Seq Library Prep Kit 2.0
QIAGEN QIAseq FX DNA
Roche KAPA HyperPrep
Roche KAPA HyperPlus
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Transcriptome Sequencing
Want to dive deeper into the genetic makeup of your samples? Transcriptome sequencing is the key to gene expression and regulation! This advanced technique allows you to sequence and analyze all of your RNA transcript samples, providing invaluable insight into how genes are turned on or off.
Our state-of-the-art transcriptome sequencing services utilize cutting-edge technology to provide you with accurate and reliable data. We offer a range of methods to meet your specific research needs, including:
Transcriptome Sequencing
Illumina TruSeq Stranded Total RNA
Illumina Stranded Total RNA Prep Ligation with Ribo-Zero Plus
Illumina TruSeq Stranded mRNA
Illumina Stranded mRNA Prep and Ligation
Lexogen QuantSeq 3´mRNA-Seq Library for Illumina
NEBNext Ultra II Directional RNA (rRNA depletion)
NEBNext Ultra II Directional RNA (Poly(A) mRNA isolation)
Roche KAPA RNA HyperPrep
Roche KAPA mRNA HyperPrep
Takara SMART-Seq HT
Our team of experts will work with you to customize the sequencing process and provide you with high-quality data and comprehensive analysis. With our transcriptome sequencing services, you can unlock a wealth of information about gene expression and regulation, leading to new insights into disease mechanisms and potential therapeutic targets.
Contact us today to learn more about our transcriptome sequencing services and how we can help you advance your research goals and translate the latest genomics research into actionable insights.
Additional Resources for the Hamilton NGS STAR
Download NGS STAR Flyer now
See all Hamilton Robotics Automated Liquid Handlers
View all of Hamilton's Assay Ready Workstations
Check out the Hamilton Microlab STAR automated liquid handler
Specific Applications
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Whole Genome and Transcriptome Analysis for Leukemia Diagnostics
Automation of the NGS assay helps to improve and enhance productivity by minimizing bias that might otherwise be introduced when preparing libraries manually. Moreover, the automated system is flexible enough to adapt and therefore easily meet evolving needs. -
Automated Nucleic Acid Extraction for Pathogen Detection using ROBOSCREEN‘s Rapid INSTANT Virus RNA/DNA Kit
Molecular testing of clinical samples for viral pathogens has already long become standard in both research and diagnostic laboratories. Every molecular biological test relies on high-quality sample material to achieve the best possible sensitivity and specificity. Therefore, the first step of sample analysis – the extraction of viral RNA and DNA – is of the utmost importance for the final result. -
Oxford Nanopore Genomic DNA by Ligation XL Protocol on NGS STAR 96
Sequence-based surveillance of circulating pathogens gives us important information about the spread and transmission networks of those diseases, as well as insight into emerging variants. Not only does this data help scientists to discover how viruses adapt and evolve, but it can also be used to assess the efficacy of vaccines—or inform new vaccine formulations. -
Automation of Long-Read Sequencing Library Preparation with PacBio SMRTbell prep kit 3.0 on Hamilton NGS STAR MOA
Advancing scientific discoveries, at scale, requires complete sequencing data, as well as suitable workfl ows to address high-throughput needs. Long-read sequencing technologies are quickly becoming the new gold standard to explore the full extent of genetic variation.

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Whether you need a new instrument or support for one already in the lab, Hamilton is here to support you. Dedicated staff around the world are ready to respond to your request.
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