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Drug Compound Purification

drug compounds

More than 70% of all drug compounds are organic bases that carry a partial to full positive charge at pH 7.  The flexibility to employ alkaline pH and high temperature is of immense value.  The PRP-C18 reversed-phase HPLC column is well suited to handle prolonged exposure to elevated temperatures, even at high pH.   This gives researchers the power harness both elevated temperature and high pH to facilitate resolution between closely-related drug compounds and their degradation products.