PIPEJET® Nano Dispenser
Drop-on-Demand
2–70 nL
Nanoliter Dispensing
Precise
<3% CV
Repeatable
Easy Setup
No Liquid Classes
Non-Contact
Simplified Liquid Handling
No liquid class calibration required. Just load your liquid and start dispensing, even with challenging or unfamiliar fluids.
Use case
How It's Used
PIPEJET® technology is used across a broad range of life science and industrial applications, including cell and tissue technologies, drug discovery, diagnostic test development, biosensor fabrication, microarrays, and material science. Whether integrated into Hamilton BIOSPOT® liquid handlers or OEM systems, PIPEJET®supports precise, non-contact nanoliter dispensing with minimal sample loss.
References
Next-Level Dose-Response Assays with BIOSPOT: Precision and Efficiency in Compound Curves
BIOSPOT® simplifies dose-response curve generation with the…
Non-contact microneedle coating utilizing drop-on-demand PIPEJET technology
Read this application note showcasing advanced non-contact…
BIOSPOT® Workstation: Elevating Cell-Based Toxicity Assays with Nanoliter Precision
Automate dose-response curves with BIOSPOT®: precise…
PIPEJET® Nano Dispenser
The core of Precise Nanoliter Dispensing
The PIPEJET Nano Dispenser is a non-contact, positive displacement technology designed for ultra-precise nanoliter droplet generation. Piezo-driven actuation ensures consistent, contamination-free dispensing across a wide range of liquids.
Integrated into BIOSPOT Platforms
PIPEJET is the core dispensing technology powering our BIOSPOT® Workstation and BIOSPOT® DX, enabling automated nanoliter dispensing onto microplates, membranes, and diagnostic substrates.
Available for OEM Integration.
Designed for flexibility, PIPEJET can be embedded into third-party systems as a robust OEM component, offering compact, scalable dispensing to streamline your workflows.
Also Offered as a Kit
For labs and integrators looking for a quick start, the PIPEJET Nano Dispenser Kit provides a plug-and-play setup with everything you need: dispenser, control unit, dosing pipe, cables, and software — all in one box.
Common applications Manufacturing, Point of Care Tests, Microneedle Coating
Featured Technologies
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Ultra-Low VolumePIPEJET®
PIPEJET® non-contact nanoliter dispensing technology
Deliver highly accurate nanoliter dispensing with piezo-actuated control, ensuring consistent, reproducible results for various liquid types.
Non-contact dispensing prevents clogging and cross-contamination, ensuring reliable dispensing for sensitive life sciences and diagnostic applications.
Dispense a wide range of liquids, from buffers to viscous or particle-laden samples, even living cells.
Begin with a standalone kit and scale to full automation by integrating PIPEJET® into platforms like BIOSPOT® ARC or OEM systems.
Engineered for Precision Integration
The PIPEJET® Nano Dispenser is built for precise nanoliter dispensing through a mechanically simple yet highly flexible design. Its compact size, modular components, and piezo-actuated positive displacement system make it ideal for assay miniaturization and OEM integration. From microtiter plate applications to custom automation, each element supports accurate, reproducible performance without requiring complex fluidics or calibration.
1
Compact 9 mm Format
With a slim 9 mm profile, the PIPEJET® fits standard 96-, 384-, or 1536-well plate formats. This compact size allows integration into dense, multi-channel dispensing systems and miniaturized workflows.
2
Piezo Stack Actuator
The core of the PIPEJET® is a piezoelectric stack that drives the system with sub-micron precision. Its fast, consistent actuation ensures high-frequency, reproducible droplet generation with minimal energy input.
3
Positive Displacement Piston
The piezo actuator controls a miniature piston that compresses the dosing pipe from the outside. This contact-free interaction displaces a precise volume of liquid to form each nanoliter droplet.
4
Interchangeable Pipe Guide
The pipe guide secures the flexible dosing pipe in position. It is modular and can be exchanged to fit various pipe diameters, enabling volume flexibility from 2 to 70 nanoliters.
5
Disposable Dispensing Pipe
The PIPEJET® uses a chemically resistant, inert polymer pipe. Deformation-based actuation ensures that no internal components come into contact with the liquid, minimizing contamination and cleaning requirements.
6
Easy Mechanical Integration
An M4 threaded interface on the top of the dispenser provides a secure mounting point, enabling fast, stable integration into custom holders or automated platforms.
Inside PIPEJET: Precision Nanoliter Dispensing Technology
Take a closer look inside PIPEJET technology, a non-contact, positive displacement system engineered for precise nanoliter dispensing across a wide range of liquids and applications.
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Feasibility Starts Here
The PIPEJET® Nano Dispenser Kit is the easiest way to explore non-contact, nanoliter dispensing. Designed for rapid setup and ease of use, the kit includes everything needed to begin dispensing immediately after installation. Simply unbox, install the software, connect the control unit, and you’re ready to dispense. Ideal for early feasibility testing or lab-based experiments, the kit offers a reliable starting point for precision workflows.
1
Mounting Tools
Includes a torque handle for precise pipe guide installation and a handling tool to safely insert or remove disposable dosing pipes.
2
Control ElectroniX 200
A compact, versatile controller that powers the PIPEJET and other dispensing technologies. Supports up to 12 channels and integrates easily via USB or serial communication
3
PIPEJET Dispenser & Pipe Guide
The core dispensing unit with an interchangeable pipe guide for flexible volume handling between 2 and 70 nL.
4
Pre-Installed Software (USB Stick)
Plug-and-play USB stick containing the Control Software for setup, protocol creation, and direct control of dispensing parameters.
5
Dispensing Pipes Set
A boxed set of 10 disposable pipes in different inner diameters (125, 200, and 500 µm), supporting a wide range of volumes and fluid types.
6
Accessories & Connections
All necessary accessories for immediate operation: liquid reservoirs, tubing, power supply, and interface cables for the Control ElectroniX unit.
PIPEJET® Nano Dispenser Specifications
PIPEJET-125 Specifications
PrintSystem Dimensions
- Height
- 3 cm (1.18 in)
- Width
- 9 mm (0.35 in)
- Depth
- 6.75 cm (2.66 in)
Volume Range 1
- Manual Calibration
- 2-12 nL
- Auto Calibration
- 3-10 nL
Dispensing Performance
- Viscosity Range 2
- 0.5-10 mPa.s
- Dispensing Frequency 3
- up to 50 Hz
PIPEJET-200 Specifications
PrintSystem Dimensions
- Height
- 3 cm (1.18 in)
- Width
- 9 mm (0.35 in)
- Depth
- 6.75 cm (2.66 in)
Volume Range 1
- Manual Calibration
- 5-18 nL
- Auto Calibration
- 7-15 nL
Dispensing Performance
- Viscosity Range 2
- 0.5-10 mPa.s
- Dispensing Frequency 3
- up to 50 Hz
PIPEJET-500 Specifications
PrintSystem Dimensions
- Height
- 3 cm (1.18 in)
- Width
- 9 mm (0.35 in)
- Depth
- 6.75 cm (2.66 in)
Volume Range 1
- Manual Calibration
- 20-75 nL
- Auto Calibration
- 25-70 nL
Dispensing Performance
- Viscosity Range 2
- 0.5-150 mPa.s
- Dispensing Frequency 3
- up to 50 Hz
1 Liquid dependent
2 At room temperature
3 Performance values based on low-viscosity fluids; results may vary with different liquid properties.
Support your entire workflow with Hamilton's integrated products.
Test PIPEJET as standalone dispensers, then scale up by integrating them into Hamilton platforms like BIOSPOT® ARC or BIOSPOT® DX. Gain access to ready-to-use gantry systems with intuitive software to build advanced, automated dispensing workflows
Test. Integrate. Automate.
Start with PIPEJET®, SIJET or SMARTDROP® as standalone tools, then scale up on BIOSPOT® ARC or BIOSPOT®DX for automated dispensing with ready-to-use gantry systems and intuitive workflow software.
PIPEJET® Nano Dispenser Resources
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Find out the best configuration for your workflow
Services
Hamilton's Dispensing Service offers feasibility testing to evaluate if your liquid and workflow are compatible with our dispensing technology.
Hamilton's Technical Support team is here to provide product trouble-shooting, repair, application support, virtual start-up support, and more.
Installation, set-up, and calibration support directly on-site. Our field service team ensures your sensors and cables are installed and functioning correctly.
Preventative maintenance and regular service contracts. Schedule on-site service dates to ensure your sensors are properly maintained and your process is optimized.
User trainings and on-site trainings for technicians. Tailored training ranging from basic operation to advanced calibration and maintenance.
Backed by world-class service and support.
For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.
Let's Talk
Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.
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