NGS STAR for Library Prep
The Premiere Solution for NGS
The NGS STAR for Library Prep assay ready workstation is a comprehensive solution for next-generation sequencing (NGS) applications from whole genome to whole transcriptome sequencing and targeted sequencing applications. Fully automated library preparation can be optimized for use with assay chemistries from leading industry partners, with throughputs up to 96 sample libraries processed at once.
Features and Benefits
Fully Optimized NGS Solution
The NGS STAR for Library Prep is ideal for multiple automated NGS library preparations. Each NGS application is optimized and qualified in collaboration with industry-leading partners such as:
- Illumina
- Roche-KAPA
- PacBio
- IDT
- Twist
- Thermo Fisher Scientific
- New England BioLabs
- SWIFT
Have specific questions, or don’t see a desired provider on this list? Contact our dedicated application experts, who will provide guidance and translate specific needs into reliable and efficient automated workflows.
Individualized Flexibility
The NGS STAR for Library Prep uses an open deck layout so that every system is fine-tuned to the lab’s specific NGS workflow, throughput and assay needs. At the same time, the system is easily updated to keep pace with protocol updates, or as requirements evolve over time.
Precise, Repeatable Liquid Handling
Air displacement pipetting using Hamilton tips with CO-RE (Compressed O-Ring Expansion) technology provides superior measurement accuracy, precision, and reproducibility without tip distortion or aerosol generation during tip pick-up and ejection.
Hands-Free, Hassle-Free Operation
As a fully walkaway system, NGS STAR for Library Prep significantly reduces cumbersome and user- or sample-variable preparation steps during runs of 1 to 96 samples. User-friendly software guides operators through the automated process, and automated barcode verification ensures proper placement of samples, reagents, plates and tips. Each aspirate and dispense step is dynamically tracked, for confidence that the indexed and multiplexed samples are processed according to the worklist and highly reproducible, even across different sites.
Specifications
All specifications are based on the Microlab STAR.
| Dimensions | |
|---|---|
| Length | 31.2 in (795 mm) |
| Width | 65.6 in (1664 mm) |
| Height | 35.6 in (903 mm) |
Common NGS Kits and Available Hamilton Methods
| Library Prep Kit | Method Availability |
|---|---|
| Agilent SureSelect XT | Method available |
| IDT xGen Enrichment | Method qualified by IDT |
| Illumina 16S rRNA | Method qualified by Illumina |
| Illumina Nextera DNA Flex | Method in development |
| Illumina Nextera Rapid Capture | Method available |
| Illumina Nextera XT DNA | Method qualified by Illumina |
| Illumina Nextera Flex for Enrichment | Method qualified by Illumina |
| Illumina TruSeq DNA PCR-Free | Method available |
| Illumina TruSeq Nano DNA | Method qualified by Illumina |
| Illumina TruSeq RNA Exome | Method qualified by Illumina |
| Illumina TruSeq Stranded mRNA | Method qualified by Illumina |
| Illumina TruSeq Stranded Total RNA | Method qualified by Illumina |
| Illumina TruSight Cardio | Method available |
| Illumina TruSight One | Method available |
| Illumina TruSight RNA Fusion | Method available |
| Illumina TruSight Rapid Capture | Method available |
| Illumina TruSight Tumor 170 | Method qualified by Illumina |
| Roche NimbleGen Target Capture | Method qualified by Roche |
| Roche/KAPA HyperPlus | Method qualified by Roche |
| Roche/KAPA HyperCap | Method qualified by Roche |
| KAPA Library Quantification Kit for Illumina | Method qualified by Roche |
Specific Applications
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Fully Automated Library Quantification for Illumina® Sequencing on the NGS STAR
In this case study, we describe a newly developed automated method for the quantification of Illumina NGS libraries using the KAPA Library Quantification Kit on the NGS STAR. -
TruSight Tumor 170 Automated on the NGS STAR for Illumina Library Prep
Hamilton Robotics and Illumina, Inc have partnered to automate the TruSight Tumor 170 library preparation kit on the NGS STAR. TruSight Tumor 170 simultaneously analyzes DNA and RNA while covering a wide range of genes and variant types. TruSight Tumor 170 is capable of producing accurate results from low-quality formalin-fixed paraffin-embedded (FFPE) samples with a minimum input requirement of 40 ng. The design of the NGS STAR, as a single configuration, enables implementation of additional methods as well as future Illumina protocols using the TruSight Oncology workflow as they are released.
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