Genomic STARlet Assay Ready Workstation

Fully Automated
Silica Membrane
Supported NA Extraction
Throughput Range
8 to 96
Samples Per Run
Processing Through
Vacuum System
Aided Filtration

Rapid, Efficient Nucleic Acid Isolation

Boost throughput and nucleic acid yield on this walkaway solution developed for membrane-based solid phase nucleic acid purification.

Rapid Vacuum-Based Nucleic Acid Isolation

The Genomic STARlet was optimized together with MACHEREY-NAGEL to quickly isolate high-quality nucleic acids using NucleoSpin and NucleoFast assay kits. This assay ready workstation leverages the Microlab STARlet as a base, with eight independent CO-RE II pipette channels and deck space to accommodate all hardware needed for walkaway processing using these and other silica membrane-based kit chemistries, along with pre-programmed and verified methods.

 Efficiency for Genomic Workflows

The Genomic STARlet provides full process integration in a small footprint to conserve precious laboratory space. Additionally, once your nucleic acid is purified using the Genomic STARlet, extend automated convenience in downstream applications using Hamilton assay ready workstations for next-gen sequencing or PCR.

Common applications Genomics, Nucleic Acid Extraction, Pharma & Biopharma, Cell Line Development, In Vitro Diagnostics

Featured Technologies

Hamilton Innovation Starts at the Channel

Liquid Handling Technology

  • MAD - Monitored Air Displacement

    For Unmatched Reliability

    MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.

    Diagram showing three pipette tip states—Normal, Empty, and Clogged—each with a corresponding pressure curve graph.
  • Dual Liquid Level Detection (LLD)

    For Accurate Aspirations

    Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.

    Infographic showing 3 common pipetting issues: vessel overflow, over aspiration, and liquid on outside the tip
  • TADM – Total Aspiration & Dispense Monitoring

    For Real-Time Pipetting Accuracy

    During aspirate and dispense steps, TADM monitors real-time pressure changes in each Hamilton liquid handler pipetting channel. Results are compared against expected values to expose anomalies like bubbles and insufficient volumes. Sample transfers are verified with a digital audit trail.

    Pressure vs. time graph showing aspiration and dispense phases with 7 labeled points across three overlapping curves.
  • Anti-Droplet Control (ADC)

    For Drip-Free Pipetting

    Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.

    Syringe diagram with plunger, pressure sensor, and volatile liquid labels; graphs showing pressure over time with droplet and oscillation patterns.
  • Pipetting Technology
    DPS - Dynamic Positioning System

    For Efficient Movements

    DPS enables all channels to pipette simultaneously, even across non-uniform patterns. Unlike fixed channels with equidistant spreading, DPS offers efficient yet flexible liquid handling for cherry picking, non-uniform and variable volume samples, and complex pipetting workflows.

  • Pipetting Technology
    Aerosol-Free Tip Ejection

    To Prevent Cross-Contamination

    As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.

  • Accessories
    Autoload

    For Convenient Identification

    Uses a 1D barcode scanner to automatically identify and verify samples, carriers, and consumables such as tips, tubes, micro plates, and reagent troughs as they are placed onto the liquid handling deck. Optional 2D barcode reading is available, and results may be sent to any LIMS for documentation.

  • Transport Solutions
    Plate Gripper

    For Flexible Integration

    Plate Grippers move labware to-and-from any position on the Hamilton automated liquid handling deck. For even greater hands-free efficiency and workflow integration, the Plate Grippers can transport plates to-and-from nearby off-deck devices (access location is platform-specific).

  • Transport Solutions
    CO-RE Gripper

    For Additional Movements

    Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.

Various sample types, including bacterial and eukaryotic cells, tissue, blood/plasma, plants, and more, may be automatically processed on the same system.

Highly repeatable and reproducible automated steps remove risks of variability and user error compared to manual methods.

Depending on the kit, up to 96 samples may be extracted simultaneously, so you can effectively leverage downstream genetic analysis.

Advanced pipetting technology monitors performance and detects issues like clots, while barcode verifications confirm proper samples, reagents, and consumables.

  • Hamilton Microlab STAR LET automated liquid handler deck with labeled consumable and reagent carrier positions
  • Hamilton Microlab STAR LET automated liquid handler deck with numbered components; item 2 highlighted, showing plate processing stations.
  • Hamilton Microlab STAR LET automated liquid handler with numbered components 1–5 highlighted on deck
  • Hamilton Microlab STAR LET automated liquid handler with numbered deck positions (1–5) including tip carriers, microplate carriers, and a barcode reader module
  • Hamilton Microlab STAR LET automated liquid handler with 5 labeled deck positions and pipetting arm

Explore the Genomic STARlet

The deckspace on the Genomic STARlet contains all necessary equipment for full walk-away automated nucleic acid extraction for silica membrane-based kit chemistries.

1

Consumable, Reagent, and Sample Storage

Ample storage space for different tips, reagent reservoirs, and tube formats.
2

Plate and Processing Positions

Carriers for the placement and pipetting of different plate formats, like PCR plates or deep well plates.
3

Active Positions for Incubation and Filtration

Two Hamilton Heater Shakers (HHSs) for temperature-controlled processing steps, and a vacuum station for efficient binding, washing, and elution in strip or plate format.
4

Transportation Tool

The Hamilton CO-RE Gripper facilitates stable and precise plate transport steps to and from any deck position.
5

Automated Loading and Scanning

Sample and reagent traceability is ensured by the fully autoloadable tray and barcode verification to prevent any mix-ups.

Genomic STARlet Specifications

Genomic STARlet Specifications

Print

System Dimensions

Height
94.5 cm (3 ft, 1.2 in)
Width
1.01 m (3 ft, 3.61 in)
Depth
1.12 m (3 ft, 8.25 in)
Hamilton Microlab STAR let automated liquid handling workstation with pipetting arm and deck loaded with labware

Transport Tools

CO-RE Gripper
Standard
Internal Plate Gripper (IPG)
Optional

Platform/Accessories

Capacity (ANSI/SLAS Positions)
25

Sample Loading and Tracking Options

Sample Loading
Automatic
Autoload Barcode Scanner (1D)
Standard

Pipetting Options

1 mL Channels
8
Pipetting Range 1
1 µL - 1000 µL

1 Depending on Configuration

Genomic STARlet Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Backed by world-class service and support.

For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.

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