PSD SmartSense

Optimized control
Intuitive SmartSense GUI
user experience and speed
Effortless setup
Autodetection of Smart Syringes and Valves
simplifies configuration
Real-time oversight
Built-in Sensor Monitoring
precise and consistent dispensing

A New Era of SMART

Unparalleled traceability, process control, data integrity, and customization. Hamilton’s new SmartSense Syringe Pump delivers it all with cutting-edge smart features. The PSD SmartSense is built upon the PSD/4 design and features a 30 mm stroke length and accommodates syringe volumes ranging from 12.5 μL to 2.5 mL.

The Hamilton PSD SmartSense is a compact, high-precision syringe pump engineered for intelligent liquid handling in OEM applications. Designed for critical environments where accuracy, reliability, and data traceability are non-negotiable, SmartSense delivers real-time diagnostics, fast data communication, and seamless integration with your system. Compatible with both Smart syringes and valves, it automatically detects volumes and components, ensuring optimal setup and reducing the risk of human error.

Available in two versions—SmartSense and SmartSense Pro—this pump handles volumes from 12.5 µL to 2.5 mL, with stroke lengths of 30 mm, delivering accuracy down to ±0.5% and precision of 0.05%. Compact in design but rich in features, it’s ideal for industries including pharma, diagnostics, food and beverage, clinical research, and environmental analysis.

Common applications Analytical Chemistry, Dilutions and Dispensing

Featured Technologies
  • Intuitive control and monitoring for precision syringe pump operations.

    The PSD SmartSense graphical user interface delivers intuitive control and real-time monitoring for PSD pumps. Designed for ease of use, it enables fast setup, precise parameter adjustments, and seamless operation—enhancing flexibility and performance across liquid handling workflows.

  • Smart Detection
    Smart Accessories Detection

    Each smart valve and syringe stores key parameters—such as flow rates, volume, pressure limits, and serial data—directly on its EEPROM memory. Once connected, the PSD SmartSense pump instantly reads this data for automatic setup, enabling faster configuration, reduced manual input, and an overall improved user experience.

  • Smart Detection
    Real-time Bubble Detection

    Utilizing high-speed optical sensors, the PSD SmartSense pump  detects air gaps as small as 0.8 mm with a response time of just 20 µs. Real-time bubble detection prevents flow interruptions and supports smooth operation in precision liquid handling workflows—critical for maintaining sample integrity.

  • Smart Detection
    Real-time Pressure Monitoring

    The pressure sensor of PSD SmartSense delivers accurate fluid pressure readings from 1 to 6 bar (absolute) to ensure process stability and prevent overpressure. This integrated sensor enables real-time pressure tracking for critical applications and helps maintain performance consistency.

  • HAM PSD Smart Sense feature 1
  • HAM PSD Smart Sense feature 2
  • HAM PSD Smart Sense feature 3

Future-Ready Liquid Handling Solutions

You can choose to integrate smart syringes and valves, a bubble sensor, and a pressure sensor individually, or you can unlock the full potential of the PSD SmartSense by using all of them together.

1

Unmatched Precision and Control

Choose between SmartSense (±1% accuracy) and SmartSense Pro (±0.5% accuracy) for ultimate precision. With up to 3.5 million microsteps per full stroke, control every fluid movement with confidence.
2

Equipped with Smart Valves and Smart Syringes

Instantly identifies syringe volume and valve type, ensuring seamless integration, faster setup, and reliable performance with no manual adjustments required.
3

Real-Time Pressure and Bubble Monitoring

Monitor pressures up to 6 bar and detect air gaps as small as 0.8 mm. Keep your workflow smooth and uninterrupted with advanced sensor technology.
Small footprint Configurable Smart Accessories Pump Status Light USB connectivity PSD SmartSense

How it Works

Syringe pumps facilitate fluid transfer between various locations. The example below demonstrates their use with a simple Y-valve, while the principle remains applicable for systems with more complex valve configurations.

Delivering greater than 99% accuracy, these positive displacement pumps are the ideal choice for handling challenging liquids. The precise liquid handling capabilities and minimal air exposure ensure consistent and reliable performance regardless of the liquid’s viscosity, vapor pressure, or temperature.

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PSD Valve Diagram
  1. 1. Plunger moves down pulling desired volume of liquid from vessel A into the syringe.
  2. 2. Valve switches to other port.
  3. 3. Plunger moves up dispensing desired volume to vessel B.

PSD SmartSense Version Comparison

 SmartSenseSmartSense Pro
Accuracy±1% @ 100% of stroke±0.5% @ 100% of stroke
Syringe Resolution (step/full stroke)Up to 1,755,418 MicrostepsUp to 3,510,836 Microsteps
Syringe Speed2.5 second to 8.12 hours stroke10 second to 16.25 hours stroke
Can Integrate with Bubble SensorsYesYes
Can Integrate with Pressure SensorsYesYes
Available Smart Syringes and ValvesYesYes

Tailored for Scientific Advancement

The PSD SmartSense Pump is versatile and designed to meet the needs of various industries and applications.

Pharmaceutical Industry

Pharmaceutical Industry PSD SmartSense

Microbiology Analysis

Microbiology Analysis PSD SmartSense

Environmental Analysis

Environmental Analysis PSD SmartSense

Food and Beverage

Food Beverage PSD SmartSense

Life Science Research

Life Science Research PSD SmartSense

In Vitro Diagnostic

In Vitro Diagnostic PSD SmartSense

Sample Preparation for Clinical Laboratories

Sample prep PSD SmartSense
Hamilton NGP Animation

Why Choose a Hamilton Syringe Pump?

As the leader in precision liquid handling, partnering with Hamilton ensures you integrate the highest quality components where you need them most. For many years, Hamilton syringe pumps have been a trusted choice for researchers, scientists, and professionals who require precise, reliable, and versatile fluid handling solutions.

The combination of high precision, chemically resistant fluid path materials, durability, and ease of use makes syringe pumps a valuable asset in a variety of liquid handling applications. Partnering with Hamilton grants you immediate access to decades of liquid handling expertise.

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From Setup to Operation

With the SmartSense application interface software, you can quickly connect and configure your pump, select and manage accessories like bubble or pressure sensors, and monitor system performance in real-time with clear graphical displays for instant insights. The smart recognition feature automatically detects compatible syringes and valves, reducing setup time and ensuring precise operation.

Once your pump is configured, you can easily send commands, adjust dispensing parameters, and control pump performance with just a few clicks.

Technical engineering drawing of a square panel module, front view, showing bolt holes, fasteners, and dimension lines.
Partner with Hamilton

Integrate Hamilton's trusted liquid handling technology into your next OEM projects

In addition to our revolutionary PSD SmartSense, Hamilton offers a wide variety of liquid handling components designed for seamless integration. Our goal is to ensure you integrate the highest quality technology where you need it most.

Work directly with our team of experts for all of your liquid handling and OEM needs.

SmartSense Specifications

SmartSense Specifications

Print
PSD SmartSense versions
PSD SmartSense
PSD SmartSense Pro
Accuracy
±1% @ 100% of stroke for PSD SmartSense
±0.5% @ 100% of stroke for PSD SmartSense Pro
Syringe resolution (step/full stroke)
up to 1,755,418 microsteps for PSD SmartSense
up to 3,510,836 microsteps for PSD SmartSense Pro
Syringe speed
2.5 second to 8.12 hours stroke for PSD SmartSense
10 second to 16.25 hours stroke for PSD SmartSense Pro
Can Integrate with Bubble Sensors
Yes
Can Integrate with Pressure Sensors
Yes
Available Smart Syringes and Valves
Yes

Backed by world-class service and support.

For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.

Let's Talk

Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.

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