Fermentation within the World of Hamilton | Flyer

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Hamilton brochure cover titled "Fermentation within the World of Hamilton" with a 3D render of green rod-shaped bacteria

Manufacturing biopharma and biotech products is a complex process requiring a design phase to create the desired genetically modified strain and the optimization of fermentation conditions to enhance process reproducibility and ensure consistent yields, while adhering to industry guidelines such as pharmaceutical Good Manufacturing Practices (GMP). 

Scale-up studies conducted in R&D labs identify optimal conditions for large-scale implementation. These conditions are achieved by monitoring Critical Process Parameters (CPPs) such as pH, dissolved oxygen, CO₂, and total cell density in real time for automated control.

  • Process Analytics
    In-line sensors for real-time monitoring of critical parameters like pH, DO, CO₂, and cell density—scalable from lab to production.
  • Automated Liquid Handling
    The mini-bioREACTOR 48 enables efficient mL-scale strain screening with precise control and real-time pH/DO monitoring—ideal for fast, cost-effective scale-up.
  • Automated Storage System
    The Verso Q20 offers -80 °C automated storage in a compact format, with full sample traceability, LIMS integration, and support for standard labware.

 

 

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