Fluid Motion Technology

More Workspace. More Performance. More Value.

What is Fluid Motion Technology?

Fluid Motion is our latest advanced liquid handling drive system. Based on our well-known and established ZEUS X1 technology, Fluid Motion directs and controls pipetting channels to ensure precise operation and performance. Our 1 mL air displacement X1 channel is the first Hamilton pipette channel to feature Fluid Motion Technology. The X1 pipette channel is user exchangeable and offers universal compatibility for effortless method transfers between Hamilton automated liquid handling systems.

Fluid Motion is also compatible with our Standard 96, TADM 96, and 384 Multi-Probe Heads.

United Technologies for Unlimited Potential

Fluid Motion technology operates in perfect harmony with our other advanced and industry-leading automated liquid handling technologies for optimal and highly repeatable pipetting results.

  • CO-RE II – Tip/Tool Attachment
  • DPS – Dynamic Positioning System
  • MAD – Monitored Air Displacement
  • Aerosol - Free Tip Ejection
  • Dual LLD – Dual Liquid Level Detection
  • TADM – Total Aspiration and Dispense Monitoring
Hamilton automated liquid handler deck with multiple CO-RE pipetting channels and an 8-channel pipetting arm mounted on gantry rails
Hamilton automated liquid handler deck with 8 CO-RE pipetting channels and robotic arm under blue LED illumination

More Room for More Innovation

With its slim, streamlined profile, Fluid Motion from Hamilton allows X1 channels or the 96 MultiProbe head to access up to 5 additional tracks on the liquid handler’s deck. With workspace access increased by as much as 16%, scientists can automate additional workflow steps and further accelerate sample processing throughput using a single platform.

These enhanced efficiencies free users from mundane, manually performed laboratory tasks to gain productivity in high-value activities. By integrating more devices on-deck and boosting throughput, Fluid Motion can also help to save valuable lab space otherwise taken up by additional manual devices.

Sample to Solution in Record Time

Because every second counts, Fluid Motion offers multiple ways to quicken the pace of your valuable work. The X1 1,000 µL pipette channels featuring Fluid Motion are user-exchangeable without special tools or repair visits to maximize processing time. They are also universal, meaning that they can be used with any of our enabled automated liquid handlers to reduce downtime and effort during method transfers and liquid class development.

Through Fluid Motion technology, pipette channel z-speeds can be varied during aspiration, which is especially useful when handling viscous, foamy, or volatile liquids or in sensitive applications like cell-based assays.

This innovative automated liquid handling drive system also enables up to 25% faster tip pickup compared to our other pipetting channels to further boost sample processing throughput speeds.

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Reach Beyond Ordinary Expectations

With extended off-deck reach enabled by Fluid Motion, our world-class Microlab STAR systems equipped with the Internal Plate Gripper can access more nearby off-deck devices than ever before.

  • Left reach up to 127 mm
  • Right reach up to 92 mm

Experience Amazing Fluid Motion Power in Automated Liquid Handlers

Fluid Motion and the X1 pipetting channel are currently available on our Microlab STAR, Microlab STAR V, and Microlab VANTAGE.

Products using Fluid Motion

The Hamilton Microlab STAR is a reliable and versatile automated liquid handling platform. With advanced features like multi-probe heads, pipetting technologies, and VENUS software, this premier liquid handling system fits your laboratory needs. Revolutionize your workflows with the STAR today!
Hamilton VANTAGE 2.0 is a cutting-edge liquid handling system with automated precision. Optimize workflows with the VANTAGE robot, all while boosting performance, safeguarding samples, and maximizing walk-away time. Discover the Hamilton VANTAGE liquid handler for your current & future needs.
Hamilton STAR V, a cutting-edge liquid handling robot, unites Microlab STAR flexibility with Microlab VANTAGE high-performance capabilities to boost efficiency. The Microlab STAR V offers speed, precision, and technology for automated liquid handling. Upgrade your lab—explore the Microlab STAR V!
Hamilton Microlab NIMBUS is a compact liquid handler that uses air displacement pipetting to achieve superior measurement accuracy. With Microlab NIMBUS, experience fast, easy to use, and superior quality pipetting in a compact system at an affordable price.
The Hamilton Microlab Prep is an affordable liquid handler perfect for automating workflows. This entry-level liquid handler supports automated PCR setup and serial dilution.
Discover More Hamilton Technologies
  • Cell Processing
    Separation Structure

    Gentle Cell Dissociation for Homogeneous Seeding

    The separation structure is integrated within the transfer tube between two Swivel Units. During cell transfer, mechanical forces gently dissociate cell aggregates into single cells without compromising cell viability. 
    This process generates a homogeneous cell suspension, enabling consistent cell distribution during seeding of new target flasks. 

  • Cell Processing
    Swivel Unit

    Scientist-Inspired Motion

    The Swivel Unit securely clamps T-Flasks and Triple Flasks, establishing a stable and closed handling interface during automated processing. The motion system is designed to replicate familiar manual handling patterns used by cell biologists. 
    Gentle liquid addition protects adherent cell layers during media exchange, while controlled, scientist-inspired mixing and swivel movements support efficient cell detachment during passaging. This combination enables reliable and reproducible flask handling across routine cell culture workflows. 

  • Liquid Handling Technology
    MagPearl Closure System

    Sterility through Magnetic Coupling

    The MagPearl closure technology enables sterile fluid transfer along the entire fluid path, from tubing connections to the T-Flask interface, through magnetically actuated valves. By eliminating open fluid paths and minimizing mechanical contact points, the system maintains a closed liquid handling environment during routine cell culture operations. This design enables sterile processing and reliable liquid transfer without the need for laminar airflow. 

  • Software
    Graphical User Interface

    For Easy Operation

    The intuitive graphical user interface (GUI) makes operation as simple as a smartphone app. Get started developing, editing, and running protocols without the need for automation or coding expertise.

  • Machine Vision
    Labware Detection and Verification

    For Fast Protocol Development

    A camera mounted on top of the workstation detects and identifies labware placed on the deck. This visual recognition simplifies the process of programming new protocols by eliminating the need to scroll through long lists of options. It also ensures accurate verification of labware during protocol execution, helping to prevent loading errors.

  • Pipetting Technology
    Clot Detection

    To Avoid Errors

    Clot Detection pipetting channels are equipped with a pressure sensor that allows for pressure monitoring during aspiration and can detect blocked tips due to clots.

  • Pipetting Technology
    Capacitive Liquid Level Detection

    For Accurate Pipetting

    Channels are equipped with capacitance sensors that detect the liquid level through capacitive Liquid Level Detection (cLLD). Hamilton’s black conductive CO-RE tips facilitate capacitance sensing with the conductivity properties tailored for the capacitive liquids.

  • Storage Technologies
    Parallel Processing

    For the highest throughput

    BiOS automation modules are designed to move simultaneously, in parallel, to complete jobs faster. Additional modules, such as a second picker, reduce job processing time and act as a built-in "spare" to minimize downtime.

  • Compliance with International Requirements

    Retractex C sensor housings meet rigorous quality standards set by international bodies such as ATEX, IECEx, UKEx, and EAC Ex.

  • Exceptional Durability and Chemical Resistance

    Select stainless steel or plastic housings, along with your choice of sealing materials, to withstand high-pressure applications or tough chemicals.

  • Long-term Performance

    Retractex C is well-suited for daily use in chemical environments thanks to minimal seal wear from its short 36 mm stroke and in-place cleaning.

  • Enhanced Operator Safety

    Enhanced Operator Safety

    Integrated safety features, including “no sensor – no insertion” and a leakage-check window, protect operators and equipment.

  • Remarkable Cleaning Efficiency

    Remarkable Cleaning Efficiency

    The patented HyCIP system uses the Ingold socket as a cleaning chamber, delivering exceptional in-place cleaning and sterilization.

  • Lasting and Reliable Operation

    Lasting and Reliable Operation

    With low seal wear, complete cleanability, and high durability, Retractex B is well-suited for demanding industrial environments.

  • Ultra-Low Volume
    PIPEJET®

    PIPEJET® non-contact nanoliter dispensing technology

  • Supports any Process Workflow

    Supports any Process Workflow

    With easy, rapid installation, customizable settings, and automated electro-pneumatic control, RetractoControl 2 supports chemistry, pharmaceuticals, and more.

  • Extends Sensor Efficiency

    Extends Sensor Efficiency

    By automating routine cleaning cycles and retracting the sensor when not needed, the sensor’s overall lifetime may be enhanced in your process.

  • Saves Time

    Saves Time

    RetractoControl 2 takes over sensor retraction and cleaning so that users can focus efforts on high-value activities and the process can continue uninterrupted.

  • Storage Technologies
    Remote Operation

    For exceptional convenience

    Our web-based INSTINCT S automated sample management software UI allows users to interface with the storage system from mobile devices such as phones and tablets.

  • Storage Technologies
    Automated Discard

    For high-throughput disposal

    Verso Dx's automated tube discard simplifies bulk removal of expired samples, allowing system operators to dispose of up to 10,000 tubes per hour.

  • Storage Technologies
    Redundant Refrigeration

    For preventing disruptions

    Fully redundant refrigeration modules on Verso Q50 and Verso Q75 provide increased system uptime. These modules maintain continuous operation in the event of primary component failure, reducing downtime and potential sample loss.

  • Storage Technologies
    Redundant Refrigeration

    For preventing disruptions

    Fully redundant refrigeration modules provide increased system uptime. These modules maintain continuous operation in the event of primary component failure, reducing downtime and potential sample loss. Helps protect long-term storage by maintaining stable storage conditions during component failures.

  • Storage Technologies
    AMR Integration

    For maximized efficiency

    Enhance your lab's workflow by integrating the automated sample storage system with an Autonomous Mobile Robot (AMR). When integrated, these specialized robots offer location independence, high flexibility, and increased output. Enables higher-throughput storage and retrieval and supports integrated sample management solutions across rooms or floors.

  • Storage Technologies
    Whisper-Quiet Operation

    For optimal focus

    The SAM HD Pro system operates at under 44 decibels. This low-volume operation helps create a workspace that is conducive to concentration and productivity.

  • Storage Technologies
    Universal Variable Drive

    For superlative performance

    Thanks to the ultra-low temperature freezer's Universal Variable Drive technology, the system adjusts its speed dynamically to ensure optimal cooling while also enhancing energy efficiency.

  • Storage Technologies
    Touchscreen Monitor

    For direct interaction

    An intuitive touchscreen monitor simplifies interactions, allows for precise control, and enhances the overall user experience. A user-friendly interface for at-a-glance status, job control, and exception handling.

  • Storage Technologies
    Customizable Picker Module

    For special applications

    Verso's dynamic versatility allows labs with uncommon workflows to customize their sample management storage system. The system's picker can be modified to accommodate newborn screening cards, DNA collection cards, or even horizontal picking. The system is ideal for specialized sample collections where non-standard formats still need automated sample handling and traceable workflows.

  • Storage Technologies
    High-Speed Sample Identification

    For faster processing

    The system is equipped with a High-Speed Sample Identification module to provide rapid and accurate sample barcode detection, giving labs the ability to further optimize their workflow.

  • Storage Technologies
    -20°C Barcode Reading

    For peak sample integrity

    To ensure the highest possible sample safety, barcodes are scanned at -20°C within the system to minimize temperature fluctuations and prevent degradation. This helps maintain sample integrity and preserves high-quality data by reducing thaw cycles and temperature swings.

  • Storage Technologies
    Tube Side Barcode Reader

    For enhanced traceability

    An optional Tube Side Barcode Scanning Module is available to identify 1D and 2D barcodes on the sides of tubes and associate that barcode information with their location in the parent rack. Improves sample tracking and supports compound library governance by associating tube identity with rack and location history.

  • Smart Detection
    Smart Accessories Detection

    Each smart valve and syringe stores key parameters—such as flow rates, volume, pressure limits, and serial data—directly on its EEPROM memory. Once connected, the PSD SmartSense pump instantly reads this data for automatic setup, enabling faster configuration, reduced manual input, and an overall improved user experience.

  • Smart Detection
    Real-time Pressure Monitoring

    The pressure sensor of PSD SmartSense delivers accurate fluid pressure readings from 1 to 6 bar (absolute) to ensure process stability and prevent overpressure. This integrated sensor enables real-time pressure tracking for critical applications and helps maintain performance consistency.

  • Smart Detection
    Real-time Bubble Detection

    Utilizing high-speed optical sensors, the PSD SmartSense pump  detects air gaps as small as 0.8 mm with a response time of just 20 µs. Real-time bubble detection prevents flow interruptions and supports smooth operation in precision liquid handling workflows—critical for maintaining sample integrity.

  • Transport Solutions
    Plate Gripper

    For Flexible Integration

    Plate Grippers move labware to-and-from any position on the Hamilton automated liquid handling deck. For even greater hands-free efficiency and workflow integration, the Plate Grippers can transport plates to-and-from nearby off-deck devices (access location is platform-specific).

  • Liquid Handling Technology
    MAD - Monitored Air Displacement

    For Unmatched Reliability

    MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.

  • Liquid Handling Technology
    LFC - Liquid Fractionation Control

    For Detecting Liquid Layers via Pressure Monitoring

    Pressure-based monitoring method to detect liquid interfaces in layered samples like centrifuged blood or liquid-liquid chemical extractions. LFC simultaneously and rapidly identifies, separates, and aliquots up to 16 samples into various labware targets. It includes full sample traceability.

  • Hamilton’s INSTINCT S sample management software powers our automated sample management platforms. This lab sample management software lets users easily run daily operations with minimal training. In addition, the InVision Data Analytics package provides robust, user-friendly reports as an optional add-on to BiOS warranties and service contracts.

  • Intuitive control and monitoring for precision syringe pump operations.

    The PSD SmartSense graphical user interface delivers intuitive control and real-time monitoring for PSD pumps. Designed for ease of use, it enables fast setup, precise parameter adjustments, and seamless operation—enhancing flexibility and performance across liquid handling workflows.

  • Liquid Handling Technology
    Dual Liquid Level Detection (LLD)

    For Accurate Aspirations

    Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.

  • Pipetting Technology
    DPS - Dynamic Positioning System

    For Efficient Movements

    DPS enables all channels to pipette simultaneously, even across non-uniform patterns. Unlike fixed channels with equidistant spreading, DPS offers efficient yet flexible liquid handling for cherry picking, non-uniform and variable volume samples, and complex pipetting workflows.

  • Pipetting Technology
    CO-RE II Tip/Tool Attachment

    The Key to Liquid Handling Workflow Excellence

    The new CO-RE II technology assures more precise tip alignment, minimizing the risk of collisions. Also, tip coupling is faster which boosts productivity. Besides tips, a wide range of Hamilton tools are applicable with CO-RE II.

  • Transport Solutions
    CO-RE Gripper

    For Additional Movements

    Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.

  • Accessories
    Autoload

    For Convenient Identification

    Uses a 1D barcode scanner to automatically identify and verify samples, carriers, and consumables such as tips, tubes, micro plates, and reagent troughs as they are placed onto the liquid handling deck. Optional 2D barcode reading is available, and results may be sent to any LIMS for documentation.

  • Pipetting Technology
    Aerosol-Free Tip Ejection

    To Prevent Cross-Contamination

    As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.

  • Pipetting Technology
    Aerosol-Free Tip Ejection

    To Prevent Cross-Contamination

    As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.

  • Liquid Handling Technology
    Anti-Droplet Control (ADC)

    For Drip-Free Pipetting

    Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.

  • Liquid Handling Technology
    TADM – Total Aspiration & Dispense Monitoring

    For Real-Time Pipetting Accuracy

    During aspirate and dispense steps, TADM monitors real-time pressure changes in each Hamilton liquid handler pipetting channel. Results are compared against expected values to expose anomalies like bubbles and insufficient volumes. Sample transfers are verified with a digital audit trail.

  • Storage Technologies
    -80°C Universal Picker

    For ultimate flexibility

    BiOS systems feature at least one -80°C Tube Picker for all sample picking and defragmentation. This picker is compatible with a wide range of labware types and multiple labware types per system, without any need for mechanical modification. Most importantly, picking occurs within a dedicated -80°C chest freezer to maintain sample temperature during picking.

  • Pipetting Technology
    MagPip

    Precision liquid handling. Maximum efficiency.

    The tubular linear drive inside our MagPip channels can accelerate at speeds that enable precise and ultra fast pipetting down to 350nL.

  • MagPore Technology

    Hamilton's Patented Magnetic Bead Technology

    Simply transfer your magnetic bead/nucleic acid (NA) suspension into the Microlab PuriFY Strips and start your run. The Microlab PuriFY will manage the entire nucleic acid clean up process using our patented MagPore technology.