Hplc Hero Group 13418

High efficiency separations at any pH

The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase has excellent mechanical and thermal stability (> 100°C), does not shrink or swell, and is completely inert to most conditions commonly encountered in reversed-phase chromatography.

The PRP-C18 is a durable and effective column for general purpose HPLC and especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries.

Oligonucleotide Purification

The properties of the PRP-C18 make it a superior column in the field of oligonucleotide purifications, providing:

  • Superior resolution for purer oligos
  • Extended column lifetime for increased productivity
  • High loading capacity for time and cost savings

Download the Datasheet

PRP-C18 Organic applications:

  • small molecules (< 2,000 mw)
  • pharmaceuticals
  • steroids
  • halides
  • vitamins
  • amino acid analysis
  • herbicides

Examples of analytes:

  • Peptides
  • DNA
  • RNA
  • Oligonucleotides
  • Vitamins
  • Steroids
  • Herbicides
  • Pharmaceutical compounds


Hamilton's knowledge base provides a range of explanatory articles, frequently asked questions, and document downloads.
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