PRP-C18 Columns

Hplc Hero Group 13418

High efficiency separations at any pH

The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase has excellent mechanical and thermal stability (> 100°C), does not shrink or swell, and is completely inert to most conditions commonly encountered in reversed-phase chromatography.

The PRP-C18 is a durable and effective column for general purpose HPLC and especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries.

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Oligonucleotide Purification

The properties of the PRP-C18 make it a superior column in the field of oligonucleotide purifications, providing:

  • Superior resolution for purer oligos
  • Extended column lifetime for increased productivity
  • High loading capacity for time and cost savings

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PRP-C18 Organic applications:

  • small molecules (< 2,000 mw)
  • pharmaceuticals
  • steroids
  • halides
  • vitamins
  • amino acid analysis
  • herbicides

Examples of analytes:

  • Peptides
  • DNA
  • RNA
  • Oligonucleotides
  • Vitamins
  • Steroids
  • Herbicides
  • Pharmaceutical compounds

PRP-C18 Columns Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Vitamin K Congeners

Application Note

Separation of Fat Soluble Vitamin K Congeners in Under 6 Minutes (PRP-C18)

With the growing utility of the K vitamin series of molecules, a need appears relevant for both food labeling of constituents and for research based separation of the natural and synthetic compounds of vitamin K.
Catechins Identified by Hamilton HPLC Column

Application Note

Spill the Tea, Catechins Identified by Hamilton’s PRP-C18

Catechins found in tea (green, white, black), are best known for their antioxidant properties. Catechins have shown to exhibit antimicrobial activity against staphylococcus, E. Coli, and H. pylori1 in addition to preventing oxidative degradation. Read our app note on catechins identified by Hamilton's PRP-C18.
The Heat is On: The Isolation of Capsaicin for Therapeutic Treatments

Application Note

The Heat is On: The Isolation of Capsaicin for Therapeutic Treatments (PRP-C18)

A comprehensive investigation of the isolation of capsaicin for therapeutic treatments.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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