PRP-3 particles come with a larger (300 Å) pore size for protein separation. No silanol groups on the resin means no irreversible protein adsorption, giving > 90% analyte recovery. This stable material also allows the use of concentrated acids, chaotropes, and even detergents to minimize problems with protein solubility.
Application Examples: Organic compounds: large molecules (> 2,000 mw), peptides, proteins, protein digests, protected and deprotected oligonucleotides, nucleic acids.
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