Prp 1

PRP-1 columns have inherent reversed-phase separation qualities that eliminate the requirement for a stationary phase coating. Hydrolysis of the stationary phase coating is often the limiting factor in column lifetime, so the lack of coating on the PRP-1 resin extends the longevity of the column. PRP-1 also have exceptional sample recovery (≥ 95%).

Application Examples: Organic compounds: small molecules (< 2,000 mw), pharmaceuticals, steroids, nucleic acids, vitamins, herbicides.

  • PRP-1 Columns

  • PRP-1 Guard Columns

  • PRP-1 Bulk Resin

Tech Center


Hamilton's knowledge base provides a range of explanatory articles, frequently asked questions, and document downloads.
Syringe Custom Built

Work with R&D engineers to customize Hamilton parts

Hamilton's "Custom Built" program puts you directly in contact with a Hamilton R&D Engineer to discuss your application and product needs. The engineer will point you to a standard solution or propose a customized solution to meet your needs.

Talk to an engineer