The PRP-X100 circumvents diverse sample matrices problems for HPLC-ICPMS methods, providing resolution of arsenic compounds.
Organic arsenic compounds added to feed stocks of chicken and poultry pose serious environmental and ecological threats. National and worldwide health organizations, such as the United States Environmental Protective Agency and the US Food and Drug Administration, have recently implemented more stringent concentration limits for arsenic species in drinking water and foodstuffs.
Analysis of arsenic species is made challenging due to diverse sample matrices. To circumvent these problems, an HPLC-ICPMS method has been developed. Resolution of arsenic compounds is achieved by ion exchange chromatography on a Hamilton PRP-X100 column, a 55% cross-linked polystyrene-divinylbenzene copolymer functionalized with quaternary ammonium anion-exchanger group. Detection is accomplished by inductively coupled plasma-mass spectrometry.