Hamilton Syringe and Needle Reference Guide
Your Guide to
Finding the Right Syringe and Needle for Your Application
The Hamilton Syringe & Needle Reference Guide gives scientists, chromatographers and engineers the knowledge to choose, use and maintain syringes with complete confidence. This 90‑page resource delves into syringe design, series differences, termination styles, needle point geometry and care guidelines, helping you make informed decisions and extend instrument life.
What’s Inside the Guide
- Learn the terminology of syringe components and explore Hamilton’s main series
- Understand the differences between microliter and gastight syringes
- Decode syringe terminations such as RN, LT, TLL and SL
- Compare needle point styles and gauges
- Follow care and maintenance best practices
- Review calibration steps and operating parameters
Choosing the Right Syringe
Selecting the appropriate syringe begins with understanding your application requirements and sample characteristics. Hamilton offers two primary syringe types: Microliter syringes for liquid-only applications and Gastight syringes for both liquids and gases.
Microliter syringes incorporate hand-fitted stainless steel plungers with precision-bored syringe barrels. The hand-fitting process enables the tightest possible seal with virtually frictionless plunger movement, resulting in minimal plunger wear and an almost unlimited useful life when properly maintained.
Gastight syringes have precision-machined PTFE plunger tips creating a leak-free seal. The tight fit allows the tip to wipe the interior of the syringe barrel clean of sample residue. This is particularly useful with heterogeneous samples, as it reduces the likelihood of deposits building up and causing the plunger to freeze.
Understanding Terminations & Needle Point Styles
Syringe terminations serve as the critical interface between the syringe barrel and needle. Options include cemented needles for permanent connections, removable needle designs for zero dead volume, and Luer configurations (Luer Tip and PTFE Luer Lock) that provide compatibility with standard fittings and metal or Kel-F hub needles. Several different Hamilton needle point styles are offered on our syringe and needle products, depending on the application. The correct point style varies depending on the intended application.
Your Challenge. Our Custom Solution
With 𝐇𝐚𝐦𝐢𝐥𝐭𝐨𝐧’𝐬 𝐂𝐮𝐬𝐭𝐨𝐦 𝐁𝐮𝐢𝐥𝐭 𝐏𝐫𝐨𝐠𝐫𝐚𝐦, you can work directly with a Hamilton R&D engineer to explore solutions tailored to your specific needs.