Hamilton MPE² module mounted on an automated liquid handler deck with microplate racks nearby

Hamilton [MPE]²

Positive Pressure
0-100 psi
Extraction
Evaporation
RT +5 °C – 60 °C
Smooth Solvent Exchange
Reagent Dispensing
50 µL – 2 mL
Quick and Efficient

Consolidate Multiple Sample Preparation Steps

The Hamilton [MPE]2 automates multiple solid-phase extraction steps in one compact, high-throughput device to enhance efficiency, consistency, and throughput.

Automated All-in-One Solution

Hamilton’s Monitored Multi-Flow Positive Pressure Evaporative Extraction Module [MPE]2 combines Solid-Phase Extraction (SPE) steps into one compact, multi-tasking device. The compact form factor, with patented dual elevator design, works as a standalone device (US only) and easily integrates onto the deck of Hamilton’s automated liquid handlers to enrich or concentrate analytes of interest in a high-throughput manner. For added convenience, the [MPE]2 accommodates many SPE cartridges as well as 24-, 48-, and 96-well plates.

Further Enhance Automated Solid-Phase Extraction

Expand your automated SPE workflow by adding optional modules to your [MPE]2 base unit.  
Optional Modules:

  • The Reagent Module doubles liquid handling efforts by leveraging the [MPE]2 for dispensing steps. It can dispense 1 mL across a 96-well in less than one minute.
  • The Evaporation Module controls and continuously monitors temperature while removing excess liquid during steps such as sorbent drying.
     

Common applications Genomics, Nucleic Acid Extraction, Protein Sciences, Protein Purification, Pharma & Biopharma

Preparing SPE samples in micro plate format increases sample prep throughput while reducing reagent consumption.

The compact all-in-one approach frees up valuable deck space while strengthening sample selectivity, quality, and reliability.

The [MPE]2 can be used as a standalone device (US only) or be integrated with a Hamilton liquid handler.

Reduce process variations and the risk of manual errors by automating your SPE workflow and freeing users to focus on higher-value tasks.

  • Hamilton MPE² module with blue perforated panel, transparent window, and open frame section on lab deck
  • Glowing blue upward arrows of varying heights against a dark background with bokeh light effects
  • Hamilton MPE² module mounted on an automated liquid handler deck with microplate racks nearby
  • Hamilton MPE² modular pipetting extension unit with slide-out tray and visible circuit board components

Explore the [MPE]2

Explore the [MPE]2

1

0-100 PSI Pressure Range

Ideal for applications like protein and nucleic acid purification, cell-based extraction, cannabinoid analysis, and more.
2

Active Monitoring

Monitors pressure and evaporation temperature to ensure consistency across experiments.
3

Dual Elevator

Accommodates most filter/collection plate heights up to 114 mm and allows for adjustment between the plates.
4

Restricted Flow Principle

Guarantees a steady flow direction from top to bottom to eliminate the path of least resistance and optimize filtration performance.
5

Optional Reagent Module

Dispenses up to seventeen different reagents across one or multiple columns.
6

Optional Evaporation Module

Provides sorbent drying at adjustable temperatures up to 60 ºC. Includes a portable needle drying module.
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