Air Displacement Pipetting Modules

Hamilton Zeus Family

Standard and Advanced Air Displacement Pipetting

Hamilton Z-Excursion Universal Sampler (ZEUS) is a fully automated, self-contained air displacement pipette. It is a ready-to-go pipetting channel module for integration into Diagnostics and Life Science instruments. It is based on Hamilton’s revolutionary air displacement pipette technology and uses disposable tips to avoid carry-over. The module is equipped with Qualitative Pipette Monitoring (QPM) which ensures precise and secure pipetting.
 

New ZEUS X1

New ZEUS X5

Explore all Air Displacement Pipetting Modules

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ZEUS has built-in algorithms for standard and advanced pipetting tasks

Automation engineers looking to integrate pipetting components have traditionally had to invest significant effort into developing algorithms to coordinate a myriad of factors. To address these project risks, Hamilton designed the ZEUS pipetting family with on-board intelligence for industry-leading precision and accuracy. ZEUS air displacement pipettes can meet your advanced and standard pipetting applications.

Qualitative Pipette Monitoring (QPM)

On the STAR Liquid Handling Platform Hamilton pioneered the art of translating pressure curves into intelligent actions. With ZEUS, the benefit of this knowledge is available for integration into any liquid handling application. Some pipetting modules are capable of reporting pressure data. However, ZEUS is the only one capable of interpreting the data and providing actionable information back to the system.

Clogged Tip Detection

If the tip clogs during aspiration the pressure will spike down. As the plunger moves, sample is not being aspirated to help equalize the pressure.
Hamilton OEM ZEUS Clot Detection

Insufficient Liquid Detection

If there is insufficient liquid in the tube, the pressure curve will start down as normal but then will return to a pressure much higher than the expected level represented by Δp in the graph. The higher pressure is a result of having less liquid in the tip due to an incomplete aspiration.
Hamilton OEM ZEUS Empty Tube

Aspiration of Foam

If ZEUS pipettes foam instead of liquid, the pressure sensor detects spikes during the aspiration. Based on the severity of the spikes, a threshold can be set for a failed aspiration.
Hamilton OEM ZEUS Foam Detection

Anti-Droplet Control for Air Displacement Pipetting

Volatile liquids like acetone and methanol can be extremely difficult to pipette using air displacement. These liquids tend to vaporize in the tip which raises the air pressure, resulting in liquid dripping from the tip. ZEUS is equipped with Anti-Droplet Control (ADC). When enabled, the pressure is monitored in the tip. As the pressure rises, the piston is retracted to equalize the pressure and prevent dripping. The illustrations show the pressure curve when ADC is on and off.

ADC OFF

Pressure reaches a maximum; a droplet is lost and pressure drops.
Hamilton OEM ZEUS ADC Off

ADC ON

Piston retracts when pressure threshold is reached so no droplet forms.
Hamilton OEM ZEUS ADC On

Air Displacement Pipetting Modules Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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