Microlab NIMBUS

Intuitive Programming
VENUS Software
Integrated On-board PC
True Random Access
4 or 8 X1 Channels
Up to 20 SBS Deck Positions
Integrated Display
Touchscreen Control
Monitor and Manage Runs

Outstanding Performance within Budget

With several configuration options, the compact Microlab NIMBUS automated liquid handler can satisfy multiple workflow needs while keeping you within budget. It’s a must-have for lab automation beginners and professionals alike.

Scientific Citations

Powerful Compact Liquid Handler

The Microlab NIMBUS offers excellent high-throughput pipetting to save time and streamline workflows. With a small footprint, it makes maximum use of minimal lab space for versatility and efficiency.

Compressed O-Ring Expansion (CO-RE) Advantage

The Microlab NIMBUS uses highly accurate air displacement pipetting. It also leverages CO-RE Technology to achieve a tight seal between the pipette channels and tips for extreme accuracy. Optional performance monitoring tools further safeguard sample and results integrity.

Configurable Base Platforms

Multiple base platforms suit a variety of needs and budgets.

  • NIMBUS4: Up to four independent CO-RE pipette channels work with tubes and plates
  • NIMBUS96: High-speed CO-RE 96 Probe Head works with 96- and 384-well plates in individual well, column row, and whole plate formats from 1–1000 µL
  • NIMBUS HD (High Density): Up to 8 independent CO-RE pipette channels feature independent Y and Z axes movements

Precision Software

VENUS 6 Software provides liquid handling workflow control and easily integrates third-party devices. With an intuitive Method Editor and drag-and-drop programming, users can quickly build methods.

Common applications Analytical Chemistry, Dilutions and Dispensing

Featured Technologies

Hamilton Technology Starts at the Channel.

Pipetting Technology

  • Fluid Motion Technology

    More Workspace. More Performance. More Value.

    Innovative drive system enhances the utilization of deck space, enabling researchers to automate more scientific experiments seamlessly within a single unit, ultimately saving valuable lab space.

    Hamilton's Fluid Motion technology
  • DPS - Dynamic Positioning System

    For Efficient Movements

    DPS enables all channels to pipette simultaneously, even across non-uniform patterns. Unlike fixed channels with equidistant spreading, DPS offers efficient yet flexible liquid handling for cherry picking, non-uniform and variable volume samples, and complex pipetting workflows.

    Automated liquid handling system dispensing blue fluid into a row of glass test tubes via multi-channel pipette heads
  • CO-RE II Tip/Tool Attachment

    The Key to Liquid Handling Workflow Excellence

    The new CO-RE II technology assures more precise tip alignment, minimizing the risk of collisions. Also, tip coupling is faster which boosts productivity. Besides tips, a wide range of Hamilton tools are applicable with CO-RE II.

    Cross-section diagram and 3D render of CO-RE II tip and stop disk, highlighting metal coupler and sealing surface (red o-ring).
  • Aerosol-Free Tip Ejection

    To Prevent Cross-Contamination

    As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.

    Multi-channel pipette head with disposable tips positioned over a rack of sample tubes on an automated liquid handling platform
  • Liquid Handling Technology
    MAD - Monitored Air Displacement

    For Unmatched Reliability

    MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.

  • Liquid Handling Technology
    Anti-Droplet Control (ADC)

    For Drip-Free Pipetting

    Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.

  • Liquid Handling Technology
    Dual Liquid Level Detection (LLD)

    For Accurate Aspirations

    Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.

  • Transport Solutions
    CO-RE Gripper

    For Additional Movements

    Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.

The compact deck offers 11, 12, or 20 ANSI/SLAS positions for plates, reagents, consumables, and devices.

Choose between different enclosure options with 4 or 8 independent channels or a 96 Probe Head for a solution that satisfies your needs and budget.

Use the optional Clean Air Protection (CAP) system with clean HEPA filtration and UV sterility to prevent contamination.

Microlab NIMBUS may be equipped with modules like shakers, temperature control, extraction devices, and stackers from Hamilton and other manufacturers.

  • Automated liquid handler pipette arms picking up tips from a black tip rack
  • Automated liquid handler pipette arms picking up tips from a black tip rack
  • Hamilton microlab NIMBUS automated liquid handlers shown with open and enclosed enclosure configurations
  • Hamilton software dashboard showing genomics, cell culture, LCMS, and ELISA workflow shortcut tiles with navigation menu
  • Hamilton microLab NIMBUS automated liquid handler with open front enclosure and deck with labware

Explore the Microlab NIMBUS

1

Advanced Pipetting Technology

Air-displacement and CO-RE Technology, along with performance monitoring tools, ensure the utmost in pipetting performance and reliability.
2

Pipetting Options

Users may select up to 4 CO-RE Channels, the CO-RE 96 Probe Head, or up to 8 CO-RE Channels.
3

Enclosure Options

Choose between different enclosure options depending on each laboratory’s unique needs and available space.
4

VENUS Software

Simplifies Microlab NIMBUS control, device integration, and method programming. It also integrates with most laboratory information management systems (LIMS).
5

Space for Optional Tools and Accessories

Add a CAP system, labware gripper, or any number of Hamilton and third-party devices to enhance assay flexibility.
Hamilton Nimbus automated liquid handler, front view, navy blue enclosure with touchscreen interface and dual-deck pipetting workspace

Flexible automation. Intelligent interaction. Proven at scale.

Fluid Motion NIMBUS brings Hamilton’s next‑generation pipetting technology and modern operator interaction to the NIMBUS platform, delivering greater deck access, faster liquid handling actions, and a more intuitive way to monitor and manage runs. Built on the proven NIMBUS architecture and powered by VENUS process control software, Fluid Motion NIMBUS combines advanced capability with operational confidence. It supports production‑ready workflows today and provides a clear, scalable path to future expansion across larger Hamilton automation systems.

Microlab NIMBUS Specifications

NIMBUS 4 Specifications

Print

System Dimensions

Height
76.9 cm to 1.24 m (2 ft, 6.28 in to 4 ft, 0.82 in)
Width
95 cm to 1.66 m (3 ft, 1.4 in to 5 ft, 5.51 in)
Depth
51.1 cm to 70.9 cm (1 ft, 8.12 in to 2 ft, 3.91 in)

General Specifications

Weight
99.8 kg

Platform Type

Open
Optional
Standard Enclosed
Standard
Extended Enclosed
Optional
Large Extended Enclosed
Optional

Transport Tools

CO-RE Gripper
Optional

Platform/Accessories

Capacity (ANSI/SLAS Positions)
11
Device Integration
Hamilton Heater Shaker, Hamilton Heater Cooler, [MPE]², Vaccum Station

Sample Loading and Tracking Options

Sample Loading
Manual
Barcode Scanner
1D

Pipetting Options

1 mL Channels
4
Pipetting Range 1
1 µL - 1000 µL

NIMBUS96 Specifications

Print

System Dimensions

Height
76.9 cm to 1.24 m (2 ft, 6.28 in to 4 ft, 0.82 in)
Width
95 cm to 1.66 m (3 ft, 1.4 in to 5 ft, 5.35 in)
Depth
51.1 cm to 70.9 cm (1 ft, 8.12 in to 2 ft, 3.91 in)

General Specifications

Weight
113.4 kg

Platform Type

Open
Optional
Standard Enclosed
Optional
Extended Enclosed
Standard
Large Extended Enclosed
Optional

Transport Tools

CO-RE Gripper
Optional

Platform/Accessories

Capacity (ANSI/SLAS Positions)
11
Device Integration
Hamilton Heater Shaker, Hamilton Heater Cooler, [MPE]², Vaccum Station

Sample Loading and Tracking Options

Sample Loading
Manual
Barcode Scanner
1D

Pipetting Options

Multi-Probe Head Option
96
Pipetting Range 1
1 µL - 1000 µL

NIMBUS HD Specifications

Print

System Dimensions

Height
76.9 cm to 1.24 m (2 ft, 6.28 in to 4 ft, 0.82 in)
Width
95 cm to 1.66 m (3 ft, 1.4 in to 5 ft, 5.35 in)
Depth
51.1 cm to 70.9 cm (1 ft, 8.12 in to 2 ft, 3.91 in)

General Specifications

Weight
113.4 kg

Platform Type

Standard Enclosed
Standard

Transport Tools

CO-RE Gripper
Optional

Platform/Accessories

Capacity (ANSI/SLAS Positions)
20
Device Integration
Hamilton Heater Shaker, Hamilton Heater Cooler, [MPE]², Vaccum Station

Sample Loading and Tracking Options

Sample Loading
Manual
Barcode Scanner
1D
2D

Pipetting Options

1 mL Channels
Up to 8
Pipetting Range 1
1 µL - 1000 µL

1 Depending on Configuration

Microlab NIMBUS Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Compare Products
Services

Trust in Hamilton’s Field Service Engineers for high-quality automated liquid handler installation, preventative maintenance, and field repairs.

From our Field Service Engineers to our compliance with regulatory standards, you can expect high quality from Hamilton.

Backed by world-class service and support.

For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.

Let's Talk

Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.

Request Type: