PRP-1 10 µm, 4.1 x 150 mm, PN: 79425

Stainless steel

Part # 79425

PRP-1 resin (PN: 79425) is a highly cross-linked poly(styrene-divinylbenzene) polymer. Unlike silica-based C8 or C18 columns, the PRP-1 column has inherent reversed-phase separation qualities without the bonded ligand on the sorbent.  

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PRP-1 10 µm, 4.1 x 150 mm, PN: 79425 Details

PRP-1 columns have inherent reversed-phase separation qualities that eliminate the requirement for a stationary phase coating. Hydrolysis of the bonded ligands such as C18 or C8 is often the limiting factor in column lifetime, so the lack of coating on the PRP-1 resin extends the longevity of the column. PRP-1 also has exceptional sample recovery (≥ 95%).

Application Examples: Organic compounds: small molecules (< 2,000 mw), pharmaceuticals, steroids, nucleic acids, vitamins, herbicides.

Scientific Citations

PRP-1 10 µm, 4.1 x 150 mm, PN: 79425 Specifications

Print
Separation Mode Reversed-Phase
Stationary Phase PRP-1
Format HPLC Column
Hardware Inner Diameter 4.1 mm
Hardware Length 150 mm
Particle Size 10 µm
USP Classification USP L21
Packing Material Type PSDVB
Pore Size 100 Å
Particle Surface Area (m2/g) 400
Pore Volume (cm3/g) 0.772
Hardware Material Stainless Steel
Max Pressure 5,000 psi
Mobile Phase Limits pH 1-13, 0-100% aqueous, organic modifier
Buffer Strength 0.0-0.5N
Temp Limits 5-85°C
Restoration Run a gradient of 100% water to 100% acetonitrile. Repeat three times
Compound Classification Organics
UOM 1 EACH

PRP-1 10 µm, 4.1 x 150 mm, PN: 79425 Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Isolation of Paclitaxel App Note

Application Note

Pick Your Poison. Isolation of Paclitaxel. (PRP-1)

The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. Though the life-saving compound was initially found in the bark, its presence was later confirmed in every part of the tree excluding the fruit. Paclitaxel, is a member of the taxane family and has been associated with the highly toxic nature of the Taxus genus.
Hemp

Application Note

Determination of Flavonoids in Hemp by Reversed-Phase HPLC (PRP-1)

Flavonoids provide health benefits and provide a more therapeutic experience with the use of cannabis.
HAM SDS PRP 1 resin dry

SDS

SDS - PRP-1 (resin, dry)

Download the Safety Data Sheet for Hamilton PRP-1 Resin (Dry), used as a filter media in HPLC applications. Includes key safety, handling, and first aid information.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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