Polymer Packings

laboratory solutions

Hamilton Polymers - Poly(styrene divinylbenzene) or PS-DVB is a robust polymer material used as the base framework for all the Hamilton polymer HPLC packing materials. The high degree of cross-linking with divinylbenzene makes the polymer bead extremely durable for high pressure applications.

Polymer columns can handle pressures over 5,000 psi, have a usable pH range of 1‐13, and can be cleaned with 1.0 M sodium hydroxide to remove strongly retained material. Swelling in organic solvents such as THF or chloroform is negligible because of the cross‐linking. PS-DVB resins can be operated at much higher temperatures as compared to silica based materials, and they provide excellent sample recoveries due to the lack of acidic silanol groups. Polymer columns are similar in retention characteristics to a C18, however, selectivity can be slightly different in some cases.

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Polymer Packings

PRP-C18
Organic compounds: Oligonucleotides, small molecules (< 2,000 mw), pharmaceuticals, steroids, halides, vitamins, amino acids, herbicides. High pH applications.
Oligonucleotide HPLC
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Polymer Packings

PRP-1
Organic compounds: small molecules (< 2,000 mw), oligonucleotides, pharmaceuticals, steroids, nucleic acids, vitamins, herbicides.
Hamilton PRP-1 HPLC Column
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Polymer Packings

PRP-3
Organic compounds: large molecules (> 2,000 mw), peptides, proteins, protein digests, protected and deprotected oligonucleotides, nucleic acids.
Hamilton PRP-3 HPLC Columns
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Polymer Packings

PRP-h5
Organic compounds: large molecules (> 2,000 mw), halogenated compounds, pharmaceuticals, protein digests, tryptic digests, proteomics.
Prp H5
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Polymer Packings

PRP-Z2

Organic compounds: small molecules (< 2,000 mw), small polar compounds, and large molecules (> 2,000 mw), small proteins, peptides, and oligonucleotides .

Prp z2
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Polymer Packings Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Tractor Spraying Pesticides on Crops

Application Note

Advanced Chromatographic Separation of Diquat and Paraquat: Longer Retention Times and Enhanced Selectivity

Hamilton's PRP-Z2 solves analytical challenges of EPA-regulated diquat and paraquat separation through enhanced design, enabling fast, robust analysis with improved throughput and reduced solvent use.
Vitamin K Congeners

Application Note

Separation of Fat Soluble Vitamin K Congeners in Under 6 Minutes (PRP-C18)

With the growing utility of the K vitamin series of molecules, a need appears relevant for both food labeling of constituents and for research based separation of the natural and synthetic compounds of vitamin K.
Allergens Contained in Balsam of Peru (PRP-C18 / PRP-1)

Application Note

Allergens Contained in Balsam of Peru (PRP-C18 / PRP-1)

In some cases it has been shown that allergies can arise from some of the individual components of the essential oil Balsam of Peru. Read our app note detailing an HPLC method that separates five components known to have allergenic properties.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

cation exchange column

Article

USP "L" Column Listings

Explore Hamilton’s qualifying USP “L” columns.
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