PRP-C18 5 µm, 4.6 x 250 mm, PN: 79677

Stainless steel

Part # 79677

PRP-C18 polymeric columns have extraordinary pH and chemical stability.  Unlike a silica C18 column, the PRP-C18 is resistant to temperatures above 100 °C. The stationary phase stands up to prolonged exposure to high concentrations of strong acids and bases, without any measurable decrease in performance or column life.  PN: 79677

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PRP-C18 5 µm, 4.6 x 250 mm, PN: 79677 Details

PRP-C18 columns have genuine pH and chemical stability. The stationary phase stands up to prolonged exposure to concentrations as high as 1 M NaOH and 1 M H2SO4, with no measurable decrease in performance. The support does not strip, bleed, or dissolve at any pH. It can therefore perform reliably and reproducibly throughout the extended life of the column, regardless of mobile phase conditions. Unlike a silica C18 column, the PRP-C18 is resistant to temperatures above 100°C.

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PRP-C18 5 µm, 4.6 x 250 mm, PN: 79677 Specifications

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Separation Mode Reversed-Phase
Stationary Phase PRP-C18
Format HPLC Column
Hardware Inner Diameter 4.6 mm
Hardware Length 250 mm
Particle Size 5 µm
USP Classification USP L21
Packing Material Type PS-DVB functionalized with C18
Pore Size 100 Å
Particle Surface Area (m2/g) 368
Pore Volume (cm3/g) 0.624
Hardware Material Stainless Steel
Max Pressure 5,000 psi
Mobile Phase Limits pH 1-13, 0-100% aqueous, organic modifier
Buffer Strength 0.0-0.5N
Temp Limits 5-85°C
Restoration Run a gradient of 100% water to 100% acetonitrile. Repeat three times
Compound Classification Organics
UOM 1 EACH

PRP-C18 5 µm, 4.6 x 250 mm, PN: 79677 Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

HAM Reference Guide HPLC Columns

Guide

Reference Guide - HPLC Columns

Learn how to choose a column, how to maximize the life of a column through proper care, cleaning, and restoration.
HAM SDS PRP C18 resin dry

SDS

SDS - PRP-C18 (resin, dry)

Download the Safety Data Sheet for Hamilton PRP-C18 Resin (Dry), used as a filter media in HPLC applications. Includes key safety, handling, and first aid information.
Glass Syringes

Application Note

Separation of Five Steroids (PRP-C18)

A reversed-phase HPLC method was developed for separation of five steroid hormones with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone) on a Hamilton PRP-C18 HPLC column.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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