Clinical NGS STARlet
Low-Mid Throughput
24
Samples Per Run
Fully IVDR Compliant
Clinical Class
Hardware & Software
Pre-Established
NGS Library Prep
Compatibility
Safe, Effective, and Reliable
When user validated as part of an overall workflow, the CE and IVDR -compliant Clinical NGS STARlet can improve clinical laboratory throughput and efficiencies.
NGS Automation for In Vitro Diagnostics
The Clinical NGS STARlet is an IVDR -compliant, fully deck-integrated, sample-to-library solution for next-gen sequencing applications. It is built on our reliable Microlab STARlet, with advanced CO-RE II Technology and performance monitoring tools to ensure high-quality liquid handling. Eight independent pipetting channels are ideal for small-to-midsize sample throughput.
Up to 24 samples may be processed simultaneously, with full workflow traceability. Easily add the Clinical NGS STARlet to a laboratory information system (LIS) to strengthen regulatory compliance, data flow, and sample traceability.
Full Flexibility for Any NGS Chemistry Vendor
As a kit vendor-agnostic NGS library preparation platform, this system supports many can aid just about any clinical genomic applications, including but not limited to targeted enrichment, whole genome sequencing, and transcriptome sequencing.
Suitable for Clinical Use
IVDR -compliant VENUS software and hardware make the Clinical NGS STARlet ideal for clinical labs, offering full control, sample tracking, and easy method transfer to streamline NGS workflows and reduce development time.
Common applications Genomics, NGS Library Prep, Pharma & Biopharma, Drug Discovery, ADME/DMPK
Featured Technologies
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Liquid Handling TechnologyMAD - Monitored Air Displacement
For Unmatched Reliability
MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.
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Liquid Handling TechnologyDual Liquid Level Detection (LLD)
For Accurate Aspirations
Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.
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Liquid Handling TechnologyTADM – Total Aspiration & Dispense Monitoring
For Real-Time Pipetting Accuracy
During aspirate and dispense steps, TADM monitors real-time pressure changes in each Hamilton liquid handler pipetting channel. Results are compared against expected values to expose anomalies like bubbles and insufficient volumes. Sample transfers are verified with a digital audit trail.
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AccessoriesAutoload
For Convenient Identification
Uses a 1D barcode scanner to automatically identify and verify samples, carriers, and consumables such as tips, tubes, micro plates, and reagent troughs as they are placed onto the liquid handling deck. Optional 2D barcode reading is available, and results may be sent to any LIMS for documentation.
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Transport SolutionsPlate Gripper
For Flexible Integration
Plate Grippers move labware to-and-from any position on the Hamilton automated liquid handling deck. For even greater hands-free efficiency and workflow integration, the Plate Grippers can transport plates to-and-from nearby off-deck devices (access location is platform-specific).
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Transport SolutionsCO-RE Gripper
For Additional Movements
Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.
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Liquid Handling TechnologyAnti-Droplet Control (ADC)
For Drip-Free Pipetting
Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.
The Clinical NGS STARlet fulfills regulatory standards, with full reagent and sample traceability to ensure accuracy and confidence in every workflow step.
Clinical NGS STARlet is equipped with IVDR -compliant hardware and software to provide you with all the necessary tools to thrive in a regulated environment.
Walkaway operation saves critical user time while delivering highly standardized and reproducible results to support downstream sequencing.
Explore the Clinical NGS STARlet
The Clinical NGS STARlet workspace includes all modules and devices required for automated library preparation workflows with full traceability.
1
On-Deck Thermal Cycler (ODTC)
Enables hands-free, evaporation-free incubation and PCR cycling processes.
2
Consumables and Reagent Storage
Securely store all tips and plates needed for the workflow on the deck.
3
Processing Positions
To streamline NGS workflows, a primary pipetting zone processes MIDI and PCR plates. It also includes a magnet plate for rapid bead-based cleanup steps.
4
Temperature and Mixing
Two Hamilton Heater Shakers and two CPAC cooling modules provide precise temperature control on deck.
5
Transportation Tool
The Hamilton CO-RE Gripper attaches to CO-RE channels to facilitate stable, precise, and hands-free plate transport steps from and to any deck position.
6
Automated Loading and Scanning
Sample and reagent traceability to prevent errors is ensured through the autoload tray and barcode verification.
Clinical NGS STARlet Resources
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Services
Trust in Hamilton’s Field Service Engineers for high-quality automated liquid handler installation, preventative maintenance, and field repairs.
Backed by world-class service and support.
For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.
Let's Talk
Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.
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