PCR Prep STARlet

Active Cooling
Temperature Control
For Sensitive Reagents
Flexible
Scalability
In 96-Well Format
Boosting
Efficiency
For PCR Setup

Hands-Free Pathogen Sample Preparation

The PCR Prep STARlet is Hamilton’s proven solution for automating pathogen test kits, with flexible compatibility for all PCR setup workflows.

Fast, Reliable, and Automated Pre-PCR Setup

The PCR Prep STARlet is engineered for fully automated PCR reaction setup, enabling scalable and efficient sample processing. It supports a wide range of reaction types and can handle multiple 96-well output plates in a single run. Designed to save time and conserve valuable lab space, it boosts throughput while maintaining high accuracy and process reliability. The automated, high-throughput sample setup workflow helps laboratories to turn around results quickly and with high confidence in results.

Designed for Efficiency

This compact assay ready workstation fully automates PCR reaction setup and is built upon Hamilton’s Microlab STARlet. Eight independent pipetting channels deliver precise and accurate liquid handling performance.   The PCR Prep STARlet is powered by VENUS software to ensure streamlined operation and seamless integration into any laboratory information management system (LIMS).
 

Common applications Genomics, PCR Set-Up, Long-String Genomics, Pharma & Biopharma, Drug Discovery

Featured Technologies
  • Pipetting Technology
    DPS - Dynamic Positioning System

    For Efficient Movements

    DPS enables all channels to pipette simultaneously, even across non-uniform patterns. Unlike fixed channels with equidistant spreading, DPS offers efficient yet flexible liquid handling for cherry picking, non-uniform and variable volume samples, and complex pipetting workflows.

  • Pipetting Technology
    Aerosol-Free Tip Ejection

    To Prevent Cross-Contamination

    As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.

  • Liquid Handling Technology
    MAD - Monitored Air Displacement

    For Unmatched Reliability

    MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.

  • Liquid Handling Technology
    Dual Liquid Level Detection (LLD)

    For Accurate Aspirations

    Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.

  • Liquid Handling Technology
    TADM – Total Aspiration & Dispense Monitoring

    For Real-Time Pipetting Accuracy

    During aspirate and dispense steps, TADM monitors real-time pressure changes in each Hamilton liquid handler pipetting channel. Results are compared against expected values to expose anomalies like bubbles and insufficient volumes. Sample transfers are verified with a digital audit trail.

  • Liquid Handling Technology
    Anti-Droplet Control (ADC)

    For Drip-Free Pipetting

    Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.

  • Transport Solutions
    CO-RE Gripper

    For Additional Movements

    Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.

Ensure optimal PCR setup while freeing time for higher-order tasks by automating repetitive, error-prone, and potentially hazardous manual pipetting steps.

Adapt single and multiplex PCR and qPCR sample setup protocols from most chemistry providers to your lab’s specific requirements and expand over time.

Achieve efficient space utilization with an all-in-one system that supports scalable PCR and qPCR setups for high-volume workflows and fluctuating demands.

Explore the PCR Prep STARlet

The PCR Prep STARlet workspace includes all modules and devices required for an automated PCR reaction setup, supporting a wide range of experimental needs.

1

Consumables Storage

Ample storage space for different tip types.
2

Input Carrier

Cooled positions to store template DNA or RNA samples and reagents. Four CPAC positions with various available adapter options for different container and plate formats.
3

Output Carrier

Cooled positions for final PCR reaction mixes. Four CPAC positions for reaction setup and save storage until further thermocycling.
4

Transportation Tool

The Hamilton CO-RE Gripper facilitates stable and precise plate transport steps from and to any deck position.

PCR Prep STARlet Specifications

PCR Prep STARlet Specifications

Print

System Dimensions

Height
90.3 cm (2 ft, 11.55 in)
Width
1.12 m (3 ft, 8.09 in)
Depth
78.1 cm (2 ft, 6.75 in)

Transport Tools

CO-RE Gripper
Standard

Platform/Accessories

Capacity (ANSI/SLAS Positions)
25

Pipetting Options

1 mL Channels
8
Pipetting Range 1
1 µL - 1000 µL

1 Depending on Configuration

PCR Prep STARlet Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Services

Trust in Hamilton’s Field Service Engineers for high-quality automated liquid handler installation, preventative maintenance, and field repairs.

Backed by world-class service and support.

For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.

Let's Talk

Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.

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