NIMBUS Presto Assay Ready Workstation
Full Automated Extraction
Magnetic Particle-Based
DNA/RNA and HMW DNA
Flexible Throughput
8 to 96
Samples Per Run
Processing Through
KingFisher Presto
For Broad Volume Range
Optimized Magnetic Bead-Based Extraction
Developed using Thermo Scientific KingFisher Presto technology, the NIMBUS Presto reduces time and variability in magnetic bead-based sample processing methods.
Automated Nucleic Acid Extraction including HMW DNA
Hamilton, together with Thermo Scientific, optimized the NIMBUS Presto as a fully automated nucleic acid extraction solution. This assay ready workstation starts with the Microlab NIMBUS, which features four independent CO-RE II pipetting channels. It integrates the KingFisher Presto System that works with magnetic rods, and is compatible with many magnetic bead-based kits and disk-based Nanobind HMW DNA extraction kits from PacBio. It also accepts just about any primary sample type.
Hands-Free Parallel Processing
A dual-position turntable enables parallel processing where one plate is processed by the magnetic head while the NIMBUS prepares and moves the second plate. This boosts both throughput and walk-away time.
Extend Data Integrity to Downstream Processes
Reliable nucleic acid purification, including high molecular weight DNA, using the fully enclosed NIMBUS Presto set a solid foundation for any number of downstream processes, especially those leveraging other Hamilton assay ready workstations.
Common applications Genomics, Nucleic Acid Extraction, Pharma & Biopharma, Drug Discovery, ADME/DMPK
Featured Technologies
-
Pipetting TechnologyDPS - Dynamic Positioning System
For Efficient Movements
DPS enables all channels to pipette simultaneously, even across non-uniform patterns. Unlike fixed channels with equidistant spreading, DPS offers efficient yet flexible liquid handling for cherry picking, non-uniform and variable volume samples, and complex pipetting workflows.
-
Pipetting TechnologyCO-RE II Tip/Tool Attachment
The Key to Liquid Handling Workflow Excellence
The new CO-RE II technology assures more precise tip alignment, minimizing the risk of collisions. Also, tip coupling is faster which boosts productivity. Besides tips, a wide range of Hamilton tools are applicable with CO-RE II.
-
Pipetting TechnologyAerosol-Free Tip Ejection
To Prevent Cross-Contamination
As part of CO-RE II technology’s functionality, pipette tips are gently ejected from each automated liquid handler pipetting channel. This prevents aerosol generation that may expose users to harmful biohazards or cross-contaminate samples and laboratory surfaces.
-
Liquid Handling TechnologyMAD - Monitored Air Displacement
For Unmatched Reliability
MAD monitors the air displacement in each pipetting channel of a Hamilton automated liquid handler. During liquid aspiration steps, this non-contact technology immediately identifies clots, empty wells, or other aspiration issues. It also delivers a confirmation of successful aspiration in each pipetting channel of a Hamilton automated liquid handler.
-
Liquid Handling TechnologyDual Liquid Level Detection (LLD)
For Accurate Aspirations
Dual LLD uses two sensors on each liquid handling pipetting channel. A capacitance sensor detects aqueous and conductive liquid surfaces while a pressure-based sensor works with non-conductive, viscous, and volatile liquids. Together, they ensure highly accurate and reliable liquid handling performance.
-
Liquid Handling TechnologyTADM – Total Aspiration & Dispense Monitoring
For Real-Time Pipetting Accuracy
During aspirate and dispense steps, TADM monitors real-time pressure changes in each Hamilton liquid handler pipetting channel. Results are compared against expected values to expose anomalies like bubbles and insufficient volumes. Sample transfers are verified with a digital audit trail.
-
Liquid Handling TechnologyAnti-Droplet Control (ADC)
For Drip-Free Pipetting
Pressure sensors on Hamilton’s pipetting channels continuously detect variations. Any changes are immediately compensated for by dosing drive movements to prevent droplet formation. Essential for high-precision and accuracy when pipetting volatile liquids like ethanol and acetonitrile.
-
Transport SolutionsCO-RE Gripper
For Additional Movements
Further streamline automated workflows with CO-RE Grippers. These agile grippers transform Hamilton's precision pipette channels into on-deck labware transport solutions on Hamilton automated liquid handlers.
Hands-free parallel processing of 24- or 96-well plates with a volume range of 50–5000 µL lets you achieve more at once and scale as necessary.
Includes pre-verified methods that support magnet-based kits from leading chemistry manufacturers and span a wide sample matrix array.
The NIMBUS Presto includes all necessary hardware along with pre-programmed methods that may be fine-tuned to specific needs if desired.
Barcode verification, along with process parameter monitoring, supports quality and regulatory requirements and helps to prevent time-consuming errors.
Explore the NIMBUS Presto
Optional Description: Set a solid foundation for various downstream processes and achieve top-quality target nucleic acid yields with hardware supporting full walk-away workflows.
1
KingFisher Presto Device
Interchangeable heads with 24 or 96 Magnetic Rods enable magnetic particle processing with KingFisher consumables. Also includes a dual position turntable and heating block.
2
Plate and Tip Storage
Dedicated positions for KingFisher deep-well plates and tip combs as well as for Hamilton pipetting tips.
3
Configurable Sample Loading Area
Primary sample container loading supports small and large tubes or plate input formats, across 6-tracks.
4
Reagent and Processing Positions
Dedicated locations for reagent storage in tubes, small and large reservoirs. Two plate processing positions for pipetting steps.
5
Transportation Tool
The Hamilton CO-RE Gripper facilitates stable and precise plate transport steps from and to any deck position.
6
Automated Loading and Scanning
Sample and reagent traceability is given by the fully autoloadable tray and barcode verification to prevent any mix-ups.
NIMBUS Presto Specifications
NIMBUS Presto Specifications
PrintSystem Dimensions
- Height
- 83.1 cm to 1.24 m (2 ft, 8.72 in to 4 ft, 0.82 in)
- Width
- 70.9 cm (2 ft, 3.91 in)
- Depth
- 1.36 m (4 ft, 5.5 in)
Transport Tools
- CO-RE Gripper
- Standard
Sample Loading and Tracking Options
- Sample Loading
- Manual
Pipetting Options
- 1 mL Channels
- 4
- Pipetting Range 1
- 1 µL - 1000 µL
NIMBUS ID Presto Specifications
PrintSystem Dimensions
- Height
- 83.1 cm to 1.24 m (2 ft, 8.72 in to 4 ft, 0.82 in)
- Width
- 70.9 cm (2 ft, 3.91 in)
- Depth
- 1.36 m (4 ft, 5.5 in)
Transport Tools
- CO-RE Gripper
- Standard
Sample Loading and Tracking Options
- Sample Loading
- Manual
Pipetting Options
- 1 mL Channels
- 4
- Pipetting Range 1
- 1 µL - 1000 µL
1 Depending on Configuration
NIMBUS Presto Resources
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Services
Trust in Hamilton’s Field Service Engineers for high-quality automated liquid handler installation, preventative maintenance, and field repairs.
Backed by world-class service and support.
For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.
Let's Talk
Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.
Request Type: