Manufacturing
Hamilton offers advanced non-contact dispensing technologies, SIJET, PIPEJET, and VALVEJET, for picoliter to microliter liquid handling. Our smart manufacturing industry solutions enable precise reagent deposition, surface modification, and microfluidic processing across manufacturing workflows, enhancing productivity and accuracy. From R&D to high-throughput production, we partner with you to provide scalable, tailored integration with vision-based process control and Quality Control (QC).
How Hamilton Supports Manufacturing Workflows
Manufacturers design, build, and deliver finished products that meet specific industry or customer needs. At Hamilton, we develop precision liquid handling instruments with non-contact, ultra-low volume liquid dispensing technologies used in the manufacturing of Point-of-Care tests, lab-on-a-chip devices, biosensors, and pharmaceutical coatings, enabling reproducibility, quality control, and throughput.
An example of advanced manufacturing is the production of biosensors or microneedle drug delivery systems by dispensing very small amounts of liquid to a target position. The required exact reagent deposition is achieved using Hamilton's non-contact dispensing technologies, such as SIJET and PIPEJET, for picoliter-to-nanoliter accuracy.
Learn more about the way we work:
- Define dispensing challenges (liquid type, volume, accuracy, throughput)
- Collect key specifications to align with your production goals
- Collaborate with R&D to outline the best approach
- Conduct a feasibility study with your specific reagents
- Analyze dispensing behavior to optimize consistency and reduce variation
- Provide performance feedback & early-stage realization concept
- Offer dispense technology stress test for validation: SIJET (picoliter), PIPEJET (nanoliter), VALVEJET (sub-microliter–microliter)
- Work closely with you to select the optimal dispensing system based on performance
- Define production scale & throughput needs (low-medium vs. large-scale)
- Adaptation of software and integration requirements
- Develop initial proof-of-concept tailored to the application in-house or in collaboration with trusted integration partners
- Optimize throughput & reagent dispensing precision to maximize your productivity and reduce costs
- Test and refine the prototype for full-scale production readiness
- Leverage vision-based drop detection for real-time volume verification
- Use substrate imaging and fiducial (reference marker) recognition to ensure accurate reagent placement
- Manufacture and assemble precision dispensing modules in-house or in collaboration with trusted integration partners
- Perform rigorous quality control to ensure accuracy and reliability
- Scale-up production to meet volume requirements
- Seamlessly integrate into your workflow with tailored software and an adaptive API
- Provide training, support, and optimization services
- Enable process monitoring and continuous improvement
- Enable traceability and support quality control across production batches
Explore Hamilton Products for Key Manufacturing Sub-applications
Overview of Common Techniques Used in Manufacturing
At Hamilton, we combine advanced manufacturing and smart process control with cutting-edge dispensing technologies to support scalable, precision workflows.
Our proprietary non-contact dispensing technologies, SIJET for picoliter volumes, PIPEJET for nanoliter dispensing, and VALVEJET for higher volumes, are engineered for seamless integration into your specific applications, including microfluidic chip production, cartridge filling, diagnostic assay assembly, and pharmaceutical applications.
Hamilton’s process control is built around a vision-based system that combines drop volume verification with substrate imaging. Cameras monitor individual droplets in real time, enabling precise feedback to immediately correct dispensing accuracy and ensure consistency on volume, trajectory, and placement.
For quality assurance, substrates are scanned post-dispensing to verify reagent deposition. This dual-layered visual control ensures reproducibility and supports traceability in Good Manufacturing Practice (GMP)-regulated environments.
Where Hamilton Manufacturing Solutions Are Used (Industries and Purposes)
Our advanced technologies enable surface modification, assay miniaturization, and free deposition of reagents with ultra-low volume accuracy. Our solutions support a wide range of applications, from diagnostics to drug discovery and development. Our technologies integrate seamlessly into R&D, pilot production, and high-throughput manufacturing workflows.
Our dispensing solutions are ideal for manufacturing diagnostic devices such as Point-of-Care (PoC) tests, biosensors, lateral flow assays (LFAs), and lab-on-a-chip formats. With solvent-free reagent deposition and customizable diagnostic layouts, we ensure consistent performance, reproducibility, and high-throughput capability for scalable healthcare production.
Our ultra-low-volume dispensing supports biosensor production, reagent spotting, and assay-ready plate preparation with ultra-low-volume precision. Our technologies optimize sample volume usage and enable assay miniaturization, which is crucial for increasing throughput and reducing reagent consumption in the life science manufacturing sector.
Hamilton’s liquid deposition systems enable precise reagent dosing for pharmaceutical manufacturing, including coating for microneedle drug delivery systems and vaccine formulation. Our non-contact dispensing reduces waste, improves reproducibility, and supports reduced-cost reagent use across clinical and commercial production environments.
Our technologies are suited for sensor production, thin-film coatings, and specialty surface treatments. With non-contact deposition and flexible integration, we collaborate with you to customize solutions that support sensor surface modification and complex industrial processes requiring high accuracy, adaptability, and reliability at scale.
Other Manufacturing Resources
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
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