Polymer Packings | Laboratory

Hamilton Polymers - Poly(styrene divinylbenzene) or PS-DVB is a robust polymer material used as the base framework for all the Hamilton polymer HPLC packing materials. The high degree of cross-linking with divinylbenzene makes the polymer bead extremely durable for high pressure applications.

Polymer columns can handle pressures over 5,000 psi, have a usable pH range of 1‐13, and can be cleaned with 1.0 M sodium hydroxide to remove strongly retained material. Swelling in organic solvents such as THF or chloroform is negligible because of the cross‐linking. PS-DVB resins can be operated at much higher temperatures as compared to silica based materials, and they provide excellent sample recoveries due to the lack of acidic silanol groups. Polymer columns are similar in retention characteristics to a C18, however, selectivity can be slightly different in some cases.

PRP-C18

Organic compounds: Oligonucleotides, small molecules (< 2,000 mw), pharmaceuticals, steroids, halides, vitamins, amino acids, herbicides. High pH applications.

PRP-1

Organic compounds: small molecules (< 2,000 mw), oligonucleotides, pharmaceuticals, steroids, nucleic acids, vitamins, herbicides.

PRP-3

Organic compounds: large molecules (> 2,000 mw), peptides, proteins, protein digests, protected and deprotected oligonucleotides, nucleic acids.

PRP-h5

Organic compounds: large molecules (> 2,000 mw), halogenated compounds, pharmaceuticals, protein digests, tryptic digests, proteomics.

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