Genomics
Genomics is the study of an organism's complete set of DNA and RNA—its genome and transcriptome. By analyzing entire genomes and transcriptomes, genomics reveals the molecular mechanisms that drive biological processes and how they influence traits across diverse biological contexts. This field is crucial to virtually all aspects of life science, as it provides detailed insights into genomic variation, gene expression, regulatory processes, and molecular interactions. By understanding this information, genomics helps address complex biological challenges and paves the way for breakthrough discoveries in genomic medicine, agriculture, environmental science, and many others.
How Hamilton Supports Genomic Workflows
The following steps and technologies are essential to modern genomic research workflows:
| Blood Fractionation | Separating blood into components like plasma or buffy coat for targeted analysis. |
| Aliquoting | Dividing samples into smaller portions to reduce freeze-thaw cycles, preserving quality. |
| Nucleic Acid Extraction | Isolating high-quality DNA and RNA for downstream analysis |
| (q)PCR Preparation | Amplification (and quantification) of specific DNA/RNA sequences with high sensitivity. |
| Next-Generation Sequencing (NGS) | Performing high-throughput, massively parallel DNA or RNA sequencing with exceptional accuracy and depth. |
| Optical Genome Mapping (OGM) | Unbiased, genome-wide visualization of structural variants with unmatched resolution across the full size continuum. |
| Nucleic Acid Storage | Maintaining DNA/RNA integrity through controlled storage and stabilization |
Hamilton supports these workflows with both flexible and standardized genomics solutions that streamline from start to finish. In addition to our fully customizable automation platforms, we offer a range of standardized Assay Ready Workstations (ARWs) to automate biologically pre-tested methods in your laboratory workflows, both quickly and easily.
Hamilton genomic products cover the full range of applications, from sample pre-processing and aliquoting to nucleic acid extraction and downstream applications such as PCR, NGS library preparation, and Optical Genome Mapping (OGM). Additional downstream applications are enabled by open platform configuration options.
The processes can be enhanced by automated quantification and normalization, and accompanied by automated sample storage for complete end-to-end solutions.
Apart from fully integrated automated processing, Hamilton also offers a wide range of manual and semi-automated tools, including our manual pipettes, syringes, and devices, allowing your lab to scale workflows based on specific
Explore Hamilton Products for Key Genomics Sub-applications
What is the Difference Between Genomics and Genetics?
Genomics and genetics are closely related but differ in scope and approach.
Genetics looks at individual genes and how they are passed from generation to generation. It helps explain how specific gene variations can affect traits like eye color or disease risk.
Genomics studies the complete set of DNA in a living organism, also known as the genome. Instead of focusing on one gene at a time, genomics looks at how all genes or large sets of genes, and the regions between them, work together. This includes studying gene expression, non-coding DNA, and how different parts of the genome interact to affect complex traits.
Genomics is part of a larger group of scientific fields called the “-omics” sciences, which study different parts of biology at a global level:
- Transcriptomics - all RNA molecules
- Proteomics - all proteins
- Metabolomics - all metabolites
- Epigenomics - all DNA or histone modifications
- Microbiomics - all microorganisms
Where Genomics Is Used (Industries and Purposes)
Genomics is a rapidly growing area in life science that continues to transform many segments in research and applied fields.
It comprises an ever-growing toolbox of methodologies to comprehensively study genetic information within organisms to provide insights relevant to:
Help diagnose disease, predict health risk, and guide personalized treatment.
Enhance understanding of disease mechanisms, discover new biomarkers and therapeutic targets to develop novel drugs or vaccines. Drive innovation in bioproduct development and synthetic biology.
Optimize crop yield, resistance, and nutritional content, enabling efficient breeding while ensuring food security and animal health.
Assess genetic diversity, track population dynamics, and monitor ecosystems. Identify at-risk species and guide preserving strategies and conservation projects.
Analyze genetic evidence to aid in identifying individuals, solving crimes, and establishing familial or ancestral relationships.
Identify pathogens, track outbreaks, understand resistance mechanisms, and accelerate the development of diagnostic tools, treatments, or vaccines. Track pollutant impacts, monitor wildlife populations and ecosystems, or evaluate climate change.
Genomics Case Studies and Application Notes
Other Genomics Resources
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Browse app notes, user guides, specification documents, and more in our Knowledge Center.
Backed by world-class service and support.
For over 75 years, the Hamilton name has been recognized globally for its unwavering commitment to quality. That pledge extends to creating long-term customer partnerships. We're proud to offer in-depth training courses, on-site field support, custom product builds, and so much more.
Let's Talk
Connect with a Hamilton expert to discuss solutions for your workflow. We are here to enable your success.
Request Type: