Biobank applications

Biobanking

Biobanking encompasses the collection, processing, storage, and distribution of biological samples, such as blood, tissues, or DNA, and associated data for research, diagnostics, or therapeutic development. Biobanks typically store thousands to millions of biological specimens, depending on their scope, research focus, and institutional capacity. 

Automated biobanking systems help improve throughput, maintain high-quality sample integrity, and streamline critical processes like automated aliquoting, storage, and sample retrieval.

How Hamilton Supports Biobanking Workflows

The following steps and technologies are essential to modern biobanking workflows:

StepDescription
Primary Sample ProcessingIdentification and qualification of primary samples to ensure consistency and prepare them for downstream steps.
AliquotingDividing samples into smaller portions to reduce freeze-thaw cycles, preserving quality.
Fast FreezingRapid freezing prevents degradation of proteins, lipids, and nucleic acids and preserves sample integrity.
Long-Term StorageSafe and secure storage of samples for future use. 

Sample processing is made easy with our state-of-the-art product portfolio of automated liquid handlers for aliquoting, fractionation, and downstream steps (e.g., nucleic acid extraction or LC-MS sample prep).

Various automated storage options, ranging from room temperature to –80 °C, can be seamlessly integrated so that sample quality assurance and integrity are maintained throughout the process, and a complete audit trail is available.

Our specialized decapping and recapping solutions allow for the automated handling of sample tubes and storage vials from start to finish. Stored samples can later be automatically retrieved for clinical or research use based on specific requests from researchers or healthcare professionals.

By integrating Hamilton advanced automation into your biobanking workflows, you can enhance efficiency, precision, and reproducibility—while supporting compliance and reducing manual errors.

Explore Hamilton Products for Key Biobanking Sub-applications

Good to Know

This section provides a selection of additional resources related to the application described on this page. It includes helpful articles, videos, and blogs that offer deeper insights into the topic.

Useful Links:

External resources not written by Hamilton but valuable for understanding the topic, such as industry guidelines, explanatory videos, or relevant tools.

Biobanking at a glance: the All of Us Biobank Watch Video
Explore how the Mayo Clinic uses an automated biobanking workflow to store up to 35 million samplesWatch Video
Learn how large biorepositories can advance personalized medicineWatch Video

Hamilton Products in Action:

A collection of videos showcasing Hamilton products in use, providing practical insights into their functionality and benefits.

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Where Is Biobanking Used?

Biobanks are used for a wide range of applications and can be categorized into different types, each addressing unique scientific, clinical, or conservation needs:

population-based biobank

Population-based biobanks collect human biological samples and associated lifestyle or environmental data from healthy volunteers to study the relationship between genetic information, lifestyle, and disease development. They aim to identify risk factors and inform preventive healthcare and public health policies. This type of biobank is often part of a large-scale government or academic initiative, such as the UK Biobank or "All of Us" in the U.S., and is highly standardized to support long-term cohort studies.

Clinical diagnostics automation

Hospital-based biobanks store biological samples collected during routine patient care or clinical procedures (e.g., surgeries) for translational research, drug development, and diagnostics. They connect clinical data with biological samples to support precision medicine initiatives. These biobanks are typically operated within hospital pathology departments, clinical research units, or academic medical centers and are closely linked to patient care, medical research, and clinical studies.

Primary sample preparation

Disease-based biobanks focus on collecting samples from patients with specific diseases to identify biomarkers, understand disease mechanisms, and develop targeted treatments. Their goal is to support disease-specific research and therapeutic advancements. These biobanks are often managed by academic institutions, disease-focused research organizations, or nonprofit consortia, often in collaboration with hospitals and specialized research groups.

panda bear

Conservation Biobanks collect and store biological samples from wild and captive animals to support biodiversity conservation, genetic research, and species preservation. They help monitor genetic diversity, study disease outbreaks, and assist in breeding and reintroduction programs for endangered species. Typically operated by conservation groups, research institutions, and zoological facilities, such as the Frozen Zoo or the Global Genome Biodiversity Network, Wildlife Genetic Resource Banks (GRBs) often collaborate with government agencies and wildlife preservation programs.

Seed biobanking

Seed Biobanks store and preserve seeds from wild and cultivated plant species to maintain genetic diversity, safeguard against biodiversity loss, and support agricultural research. They aim to protect plant species from extinction and provide resources for future food security and ecosystem restoration. Often managed by botanical gardens, government research institutions, and agricultural organizations, such as the Svalbard Global Seed Vault and national seed banks, ensuring long-term conservation and accessibility for research and reforestation projects. 

Other Biobanking Resources

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

Browse app notes, user guides, specification documents, and more in our Knowledge Center.

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