Single-Use pH Probes — OneFerm
Still Using Reusable pH Sensors in Single-Use Applications?
Hamilton OneFerm sensors are the next step in the evolution of single-use measurement. Their design solves some of the issues that commonly occur with reusable pH sensors that are inserted into the bag.
Specifically, Hamilton's single-use pH probes combine the reliability and measurement stability of our long-term proven conventional sensors with the ease of use as an integral part of the bioreactor. The sensors retain the high accuracy performance even after gamma irradiation and a sufficient shelf life making it the ideal single-use solution.

OneFerm - Traditional

OneFerm - Arc
Learn More About Our Single-Use Sensors
Trusted Design
Optical vs. Glass: Which is the Best Technology for Single-Use pH?
The glass pH electrode is widely considered the most robust and reliable device available for pH measurement. Yet, traditional glass sensors are not designed for a single-use environment because they require laborious handling and increased risk of contamination.
While optical technology exists for single-use pH measurement, that technology has not delivered the reliable accuracy that bio-process engineers depend on.
By contrast, Hamilton's single-use OneFerm pH sensors feature the high-accuracy and performance of a traditional glass pH electrode, even after gamma irradiation and dry storage.
Anatomy of OneFerm pH

Criteria | Description |
---|---|
Shaft length options |
70 mm, 120 mm, 225 mm, 325 mm, 425 mm |
Electrical Connector |
K8, VP6 (traditional) / VP8 (Arc) |
Temperature Sensor |
PT100, PT1000 (traditional) / NTC 22 kOhm (Arc) |
pH measuring range |
3–10 |
Drift |
< 0.1 pH / week |
Wetted Parts |
Glass / VMQ (Silicone elastomer) |
Explore Hamilton's Entire Single-Use Portfolio

Designed Specifically to Meet Your Single-Use Requirements
Our single-use sensors combine the reliability and measurement stability of our long-term proven conventional sensors with the ease of use as an integral part of the bioreactor. The sensors retain the high accuracy performance even after gamma irradiation and a sufficient shelf life making it the ideal single-use solution.
How Do I Purchase OneFerm Sensors?
Hamilton single-use sensors are currently only available to integrators such as bag, bioreactor, and downstream skid manufacturers.
- Bioreactor, bag, and downstream skid manufacturers are encouraged to contact Hamilton to discuss integration opportunities.
- End-users at biopharmaceutical companies are encouraged to ask their single-use solution provider if Hamilton sensors are available for their installation.

Resources
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Catalog - Process Analytics
Download the Process Analytics sensor catalog to learn about the complete offering of Hamilton process sensors and accessories. -
Brochure - Arc Intelligent Sensors
Arc Intelligent sensors offer a new way to connect to your process control system. -
Manual - OneFerm pH Sensors
Manual for OneFerm pH single use sensors describing the most important functions of this sensor.
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How do I communicate with an Arc sensor?
Arc sensors have a built-in micro-transmitter within the sensor. ArcAir software is a powerful tool to access data, configure and calibrate the sensor. This can be done with Bluetooth wireless communication or with a wired connection directly to a PC. -
How much torque is needed to install a sensor with PG13.5 threads?
Sensors with PG13.5 threads rely on the o-ring to seal against process pressure. Finger-tight (approximately 2 Newton Meter or 18 inch-lb) should be sufficient to install the sensor without leakage. Additional tightening beyond this can deform the o-ring or strip the threads.
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Comparing Glass Membrane Versus Optical pH Sensors
In biopharma applications there are two technology options for continuous pH measurement - glass membrane and optical. This article will explore both technologies along with their benefits and limitations. -
pH Sensor Design
The first commercially available glass membrane pH sensors were launched to the marketplace in the mid-1930s. The sensors of today still rely on the same design principles as these first products. -
What type of electrical connector does my sensor have?
There are multiple styles of electrical connectors used with sensors. See each style of connector and learn where they are used to decide which one fits your needs.

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